Gene: bmp7b

Basic information

Tag Content
Uniprot ID F1QD07
Entrez ID 557567
Genbank protein ID
Genbank nucleotide ID XM_005174107.3
Ensembl protein ID ENSDARP00000119798; ENSDARP00000154895; ENSDARP00000086646;
Ensembl nucleotide ID ENSDARG00000063230
Gene name Bone morphogenetic protein 7b
Gene symbol bmp7b
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MVSLLDLSAL VLSLVWGYCV LADTVFTNFT LDNEVHSSFI HRRLKSQERR EMQREILSIL 60
GLPHRPRPHL HGKHNAAPMF MLDLYNAMST EGDEEGFSYP YKPVFTTQGP PIATLQDNNF 120
LNDADMVMSF VNLVEHDKEF LPVRRHHREF RFDLSKIPEG EAVTAAEFRI YKDFVPEHFD 180
NETFRISIYQ VLEEHLDRDS DLFLLDSRVI WAAEEGWLVF DITVTSNHWV LNPGRNLGLQ 240
LALDSLDGQS VNPWVAGLVG RSGPQSKQPF MVAFFKATEV HIRSIRSAQG GNKQRNPNRS 300
KTAKGQEALR VANIAENSSA DQKQACKKHE LYVSFRDLGW QDWIIAPEGY AAYYCMGECA 360
FPLNSYMNAT NHAIVQTLVH FINPETVPKP CCAPTQLHAI SVLYFDDSSN VILKKYRNMV 420
VRACGCH 427

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologBMP7540595F1MLT0Bos taurusPredictionMore>>
1:1 orthologBMP7102177903A0A452E223Capra hircusPredictionMore>>
1:1 orthologBMP7100050299E0A9E2Equus caballusPredictionMore>>
1:1 orthologBMP7655P18075Homo sapiensPredictionMore>>
1:1 orthologBmp712162P23359CPOMus musculusPublicationMore>>
1:1 orthologBMP7458357H2QKM7Pan troglodytesPredictionMore>>
1:1 orthologBMP7492315A5GFN2Sus scrofaPredictionMore>>
1:1 orthologBmp785272G3V6W8Rattus norvegicusPredictionMore>>
1:1 orthologbmp7b557567F1QD07Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005615 extracellular space
GO:0070700 BMP receptor binding
GO:0005125 cytokine activity
GO:0008083 growth factor activity
GO:0030509 BMP signaling pathway
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0060395 SMAD protein signal transduction

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0339 Growth factor
KW-1185 Reference proteome
KW-0964 Secreted

Interpro

InterPro ID InterPro Term
IPR029034 Cystine-knot_cytokine
IPR001839 TGF-b_C
IPR001111 TGF-b_propeptide
IPR015615 TGF-beta-rel
IPR017948 TGFb_CS

PROSITE

PROSITE ID PROSITE Term
PS00250 TGF_BETA_1
PS51362 TGF_BETA_2

Pfam

Pfam ID Pfam Term
PF00019 TGF_beta
PF00688 TGFb_propeptide