Gene: msx1a

Basic information

Tag Content
Uniprot ID B3DG59
Entrez ID
Genbank protein ID AAI62283.1; AAI62290.1;
Genbank nucleotide ID
Ensembl protein ID ENSDARP00000147264
Ensembl nucleotide ID ENSDARG00000116118
Gene name Msxe protein
Gene symbol msx1a
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAPVVTMSSQ AAEEDAGVML AGQTEMQTRV TVQEDAQRPK ILPFSVEALM ADRKPSRGSP 60
DADARLAFSV EVLQLPVKAE SPERSTWVPA ARFSPSRLSP PACPLRKHKT NRKPRTPFST 120
AQLLALERKF RQKQYLSIAE RAEFSSSLSL TETQVKIWFQ NRRAKAKRLQ EAELEKLKMA 180
AKPLLPPAFG ISFPAGAHIP AYSAGSHPFH RHSANVSPVG LYTHMGYSMY HLA 233

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologMSX1102190677A0A452EK01Capra hircusPredictionMore>>
1:1 orthologMSX14487P28360CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologMsx117701P13297CPO,CLPE11.5, E13.0, E12.5, E14.0, E13.5, E14.5, E15.0, E15.5, E16.0Mus musculusPublicationMore>>
1:1 orthologMSX1461092Q2VL88Pan troglodytesPredictionMore>>
1:1 orthologMSX1F1S5G6Sus scrofaPredictionMore>>
1:1 orthologMsx1G3V6U7Rattus norvegicusPredictionMore>>
1:1 orthologmsx1aB3DG59Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0048598 embryonic morphogenesis
GO:0043049 otic placode formation
GO:0006357 regulation of transcription by RNA polymerase II

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
IPR000047 HTH_motif

PROSITE

PROSITE ID PROSITE Term
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2

Pfam

Pfam ID Pfam Term
PF00046 Homeodomain