CleftGeneDB-Search

Gene: MSX1

Basic information

Tag	Content
Uniprot ID	F1S5G6
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID	ENSSSCP00000009302
Ensembl nucleotide ID	ENSSSCG00000008727
Gene name	Homeobox domain-containing protein
Gene symbol	MSX1
Organism	Sus scrofa
NCBI taxa ID	9823
Cleft type
Developmental stage
Data sources	Homology search
Reference
Functional description
Sequence	MAPAADMTSL PLGVKVEDSA FGKPAGGAGG QTPSTTAATA AAMGADEEGA KPKVSPSLLP 60 FSVEALMADH RKPGAKDSVL AASESAQAAG GSAQPLGARP GSLGAPDAPS SPRRLGHFSV 120 GGLLKLPEDA LVKAESPEKP ERTPWMQNPR FSPPPARRLS PPACTLRKHK TNRKPRTPFT 180 TAQLLALERK FRQKQYLSIA ERAEFSSSLS LTETQVKIWF QNRRAKAKRL QEAELEKLKM 240 AAKPMLPPAA FGLSFPLGGP AAVAAAAGAS LYGASGPFQR AALPVAPVGL YTAHVGYSMY 300 HLT 303

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

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Relation	Gene symbol	Entrez ID	UniProt ID	Cleft type	Developmental stage	Species	Evidence	Details
1:1 ortholog	MSX1	4487	P28360	CPO,CL/P		Homo sapiens	Publication	More>>
1:1 ortholog	Msx1	17701	P13297	CPO,CLP	E11.5, E13.0, E12.5, E14.0, E13.5, E14.5, E15.0, E15.5, E16.0	Mus musculus	Publication	More>>
1:1 ortholog	MSX1	102190677	A0A452EK01			Capra hircus	Prediction	More>>
1:1 ortholog	MSX1	461092	Q2VL88			Pan troglodytes	Prediction	More>>
1:1 ortholog	MSX1		F1S5G6			Sus scrofa	Prediction	More>>
1:1 ortholog	Msx1		G3V6U7			Rattus norvegicus	Prediction	More>>
1:1 ortholog	msx1a		B3DG59			Danio rerio	Prediction	More>>

Showing 1 to 7 of 7 entries

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Gene ontology

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GO ID	GO Term
GO:0000902	cell morphogenesis
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001701	in utero embryonic development
GO:0002039	p53 binding
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0007517	muscle organ development
GO:0008285	negative regulation of cell population proliferation
GO:0009952	anterior/posterior pattern specification
GO:0010463	mesenchymal cell proliferation
GO:0023019	signal transduction involved in regulation of gene expression
GO:0030308	negative regulation of cell growth
GO:0030513	positive regulation of BMP signaling pathway
GO:0030900	forebrain development
GO:0030901	midbrain development
GO:0034504	protein localization to nucleus