Gene: wnt9b

Basic information

Tag Content
Uniprot ID B6V3E2
Entrez ID 565677
Genbank protein ID ACI95255.1
Genbank nucleotide ID NM_001137660.2
Ensembl protein ID ENSDARP00000055224
Ensembl nucleotide ID ENSDARG00000037889
Gene name Protein Wnt
Gene symbol wnt9b
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description Ligand for members of the frizzled family of seven transmembrane receptors.
Sequence
MCTGLPRTAC PLRLIALCIL LSHAAAYFGL TGREPLVFLP GPFANEPTNG KAHLKQCEQM 60
TLTRRQKRLC RREPGLAETL RESVRLSLLE CRYQFRNERW NCSMDGRGSL LKRGFKETAF 120
LLAVSSAALS HALAKACSSG RMERCTCDDS PGLQHREAWQ WGVCGDNLKY STKFLKKFLG 180
QKRVSKDLRA QIDAHNINVG IRAVKSGLKT TCKCHGVSGS CAVRTCWKQL SPFQDTGHLL 240
KYRYDTAVRV HSVTNSATGE TELAGPRRHS ITLPRPRPTE LVFLEESPSF CRPSRYSPGT 300
AGRPCSKDTS CSSLCCGRGY NTALRLTTLS CHCQVRWCCH VECQTCLREE EVYTCKKH 358

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologWNT9B490919J9P198Canis lupus familiarisPredictionMore>>
1:1 orthologWNT9BA0A452GA54Capra hircusPredictionMore>>
1:1 orthologWNT9B7484O14905Homo sapiensPublicationMore>>
1:1 orthologWnt9b22412O35468CLP,CLOMus musculusPublicationMore>>
1:1 orthologWNT9BA0A287BJB4Sus scrofaPredictionMore>>
1:1 orthologWnt9b303586D3ZFS0Rattus norvegicusPredictionMore>>
1:1 orthologwnt9b565677B6V3E2Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005615 extracellular space
GO:0005125 cytokine activity
GO:0005109 frizzled binding
GO:0060070 canonical Wnt signaling pathway
GO:0045165 cell fate commitment
GO:0030182 neuron differentiation

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0217 Developmental protein
KW-0272 Extracellular matrix
KW-0449 Lipoprotein
KW-1185 Reference proteome
KW-0964 Secreted
KW-0732 Signal
KW-0879 Wnt signaling pathway

Interpro

InterPro ID InterPro Term
IPR005817 Wnt
IPR026535 WNT9B
IPR043158 Wnt_C
IPR018161 Wnt_CS

PROSITE

PROSITE ID PROSITE Term
PS00246 WNT1

Pfam

Pfam ID Pfam Term
PF00110 wnt