Gene: Wnt9b

Basic information

Tag Content
Uniprot ID D3ZFS0
Entrez ID 303586
Genbank protein ID EDM06285.1
Genbank nucleotide ID NM_001107055.1
Ensembl protein ID ENSRNOP00000005074
Ensembl nucleotide ID ENSRNOG00000003807
Gene name Protein Wnt
Gene symbol Wnt9b
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description Ligand for members of the frizzled family of seven transmembrane receptors.
Sequence
MRPAPALALA ALCLLALPAV VAAAAYFGLT GREVLTPFPG PGTAAAPAQA GAHLKQCDLL 60
KLSRWQKQLC RREPGLAETL RDAAHLGLLE CQFQFRQERW NCSLEGRTGL LQRGFKETAF 120
LYAVSAAALT HALARACSAG RMERCTCDDS PGLESRQAWQ WGVCGDNLKY STKFLSNFLG 180
PKRGSKDLRA RADAHNTHVG IKAVKSGLRT TCKCHGVSGS CAVRTCWKQL SPFRETGQVL 240
KLRYDTAVKV SSATNEALGR LELWVPAKPG GPAKGLAPRP VDLVYMEDSP SFCRPSKYSP 300
GTAGRVCSRD TSCSSLCCGR GYDTQSRMVA FSCHCQVQWC CYVECQQCAQ QELVYTCKR 359

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologWNT9B490919J9P198Canis lupus familiarisPredictionMore>>
1:1 orthologWNT9BA0A452GA54Capra hircusPredictionMore>>
1:1 orthologWNT9B7484O14905Homo sapiensPublicationMore>>
1:1 orthologWnt9b22412O35468CLP,CLOMus musculusPublicationMore>>
1:1 orthologWNT9BA0A287BJB4Sus scrofaPredictionMore>>
1:1 orthologWnt9b303586D3ZFS0Rattus norvegicusPredictionMore>>
1:1 orthologwnt9b565677B6V3E2Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005615 extracellular space
GO:0039706 co-receptor binding
GO:0005109 frizzled binding
GO:0048018 receptor ligand activity
GO:0005102 signaling receptor binding
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0048754 branching morphogenesis of an epithelial tube
GO:0060070 canonical Wnt signaling pathway
GO:0045165 cell fate commitment
GO:0009267 cellular response to starvation
GO:0072044 collecting duct development
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0072046 establishment of planar polarity involved in nephron morphogenesis
GO:0001701 in utero embryonic development
GO:0001822 kidney development
GO:0060993 kidney morphogenesis
GO:0072003 kidney rudiment formation
GO:0030539 male genitalia development
GO:0072038 mesenchymal stem cell maintenance involved in nephron morphogenesis
GO:0072181 mesonephric duct formation
GO:0072164 mesonephric tubule development
GO:0072170 metanephric tubule development
GO:0072174 metanephric tubule formation
GO:1904948 midbrain dopaminergic neuron differentiation
GO:1902455 negative regulation of stem cell population maintenance
GO:0072078 nephron tubule morphogenesis
GO:0030182 neuron differentiation
GO:1905438 non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
GO:0043085 positive regulation of catalytic activity
GO:0009786 regulation of asymmetric cell division
GO:0003339 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0001932 regulation of protein phosphorylation
GO:0035150 regulation of tube size
GO:0060021 roof of mouth development
GO:0061038 uterus morphogenesis
GO:0016055 Wnt signaling pathway
GO:0060071 Wnt signaling pathway, planar cell polarity pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0217 Developmental protein
KW-1015 Disulfide bond
KW-0272 Extracellular matrix
KW-1185 Reference proteome
KW-0964 Secreted
KW-0732 Signal
KW-0879 Wnt signaling pathway

Interpro

InterPro ID InterPro Term
IPR005817 Wnt
IPR026535 WNT9B
IPR043158 Wnt_C
IPR018161 Wnt_CS

PROSITE

PROSITE ID PROSITE Term
PS00246 WNT1

Pfam

Pfam ID Pfam Term
PF00110 wnt