| Tag | Content |
|---|---|
| Uniprot ID | D3ZFS0 |
| Entrez ID | 303586 |
| Genbank protein ID | EDM06285.1 |
| Genbank nucleotide ID | NM_001107055.1 |
| Ensembl protein ID | ENSRNOP00000005074 |
| Ensembl nucleotide ID | ENSRNOG00000003807 |
| Gene name | Protein Wnt |
| Gene symbol | Wnt9b |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Ligand for members of the frizzled family of seven transmembrane receptors. |
| Sequence | MRPAPALALA ALCLLALPAV VAAAAYFGLT GREVLTPFPG PGTAAAPAQA GAHLKQCDLL 60 KLSRWQKQLC RREPGLAETL RDAAHLGLLE CQFQFRQERW NCSLEGRTGL LQRGFKETAF 120 LYAVSAAALT HALARACSAG RMERCTCDDS PGLESRQAWQ WGVCGDNLKY STKFLSNFLG 180 PKRGSKDLRA RADAHNTHVG IKAVKSGLRT TCKCHGVSGS CAVRTCWKQL SPFRETGQVL 240 KLRYDTAVKV SSATNEALGR LELWVPAKPG GPAKGLAPRP VDLVYMEDSP SFCRPSKYSP 300 GTAGRVCSRD TSCSSLCCGR GYDTQSRMVA FSCHCQVQWC CYVECQQCAQ QELVYTCKR 359 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | WNT9B | 490919 | J9P198 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | WNT9B | A0A452GA54 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | WNT9B | 7484 | O14905 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Wnt9b | 22412 | O35468 | CLP,CLO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | WNT9B | A0A287BJB4 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Wnt9b | 303586 | D3ZFS0 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | wnt9b | 565677 | B6V3E2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0039706 | co-receptor binding |
| GO:0005109 | frizzled binding |
| GO:0048018 | receptor ligand activity |
| GO:0005102 | signaling receptor binding |
| GO:0001658 | branching involved in ureteric bud morphogenesis |
| GO:0048754 | branching morphogenesis of an epithelial tube |
| GO:0060070 | canonical Wnt signaling pathway |
| GO:0045165 | cell fate commitment |
| GO:0009267 | cellular response to starvation |
| GO:0072044 | collecting duct development |
| GO:0048701 | embryonic cranial skeleton morphogenesis |
| GO:0072046 | establishment of planar polarity involved in nephron morphogenesis |
| GO:0001701 | in utero embryonic development |
| GO:0001822 | kidney development |
| GO:0060993 | kidney morphogenesis |
| GO:0072003 | kidney rudiment formation |
| GO:0030539 | male genitalia development |
| GO:0072038 | mesenchymal stem cell maintenance involved in nephron morphogenesis |
| GO:0072181 | mesonephric duct formation |
| GO:0072164 | mesonephric tubule development |
| GO:0072170 | metanephric tubule development |
| GO:0072174 | metanephric tubule formation |
| GO:1904948 | midbrain dopaminergic neuron differentiation |
| GO:1902455 | negative regulation of stem cell population maintenance |
| GO:0072078 | nephron tubule morphogenesis |
| GO:0030182 | neuron differentiation |
| GO:1905438 | non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation |
| GO:0043085 | positive regulation of catalytic activity |
| GO:0009786 | regulation of asymmetric cell division |
| GO:0003339 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis |
| GO:0001932 | regulation of protein phosphorylation |
| GO:0035150 | regulation of tube size |
| GO:0060021 | roof of mouth development |
| GO:0061038 | uterus morphogenesis |
| GO:0016055 | Wnt signaling pathway |
| GO:0060071 | Wnt signaling pathway, planar cell polarity pathway |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00246 | WNT1 |
| Pfam ID | Pfam Term |
|---|---|
| PF00110 | wnt |