| Tag | Content |
|---|---|
| Uniprot ID | J9P198 |
| Entrez ID | 490919 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_014116366.1 |
| Ensembl protein ID | ENSCAFP00000039322 |
| Ensembl nucleotide ID | ENSCAFG00000013433 |
| Gene name | Protein Wnt |
| Gene symbol | WNT9B |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Ligand for members of the frizzled family of seven transmembrane receptors. |
| Sequence | MKLPDGPLPL ACPRSYLPSS SIRPSGSLSH SLALSSLTGR EVLTPFPGLG TATAPAQGGA 60 HLKQCDLLKL SRRQKQLCRR EPGLAETLQD AAHLSLLECQ FQFRHERWNC SLEGRTGLLK 120 RGFKETAFLY AVSSAALTHT LARACSAGRM ERCTCDDSPG LESRQAWQWG VCGDNLKYST 180 KFLSNFLGPK RGSKDLRARV DAHNTHMGIK AVKSGLRTTC KCHGVSGSCA VRTCWKQLSP 240 FRETGQALKL RYDSAVKVSS ATNEALGRLE LWAPVRPGSP AKGLAPRPGD LVYMEDSPSF 300 CRPSKYSPGT AGRVCSREAS CSSLCCGRGY DTQSRLVAFS CHCQVQWCCY VECQQCVQEE 360 LVYTCKH 367 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | WNT9B | 490919 | J9P198 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | WNT9B | A0A452GA54 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | WNT9B | 7484 | O14905 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Wnt9b | 22412 | O35468 | CLP,CLO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | WNT9B | A0A287BJB4 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Wnt9b | 303586 | D3ZFS0 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | wnt9b | 565677 | B6V3E2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0039706 | co-receptor binding |
| GO:0005109 | frizzled binding |
| GO:0048018 | receptor ligand activity |
| GO:0001658 | branching involved in ureteric bud morphogenesis |
| GO:0060070 | canonical Wnt signaling pathway |
| GO:0045165 | cell fate commitment |
| GO:0009267 | cellular response to starvation |
| GO:0072044 | collecting duct development |
| GO:0048701 | embryonic cranial skeleton morphogenesis |
| GO:0072046 | establishment of planar polarity involved in nephron morphogenesis |
| GO:0001701 | in utero embryonic development |
| GO:0072003 | kidney rudiment formation |
| GO:0030539 | male genitalia development |
| GO:0072038 | mesenchymal stem cell maintenance involved in nephron morphogenesis |
| GO:0072181 | mesonephric duct formation |
| GO:0072174 | metanephric tubule formation |
| GO:1902455 | negative regulation of stem cell population maintenance |
| GO:0030182 | neuron differentiation |
| GO:1905438 | non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation |
| GO:0043085 | positive regulation of catalytic activity |
| GO:0009786 | regulation of asymmetric cell division |
| GO:0003339 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis |
| GO:0001932 | regulation of protein phosphorylation |
| GO:0035150 | regulation of tube size |
| GO:0060021 | roof of mouth development |
| GO:0061038 | uterus morphogenesis |
| GO:0016055 | Wnt signaling pathway |
| GO:0060071 | Wnt signaling pathway, planar cell polarity pathway |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00246 | WNT1 |
| Pfam ID | Pfam Term |
|---|---|
| PF00110 | wnt |