| Tag | Content |
|---|---|
| Uniprot ID | B8JKS6 |
| Entrez ID | 556870 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001101670.2 |
| Ensembl protein ID | ENSDARP00000025722 |
| Ensembl nucleotide ID | ENSDARG00000002216 |
| Gene name | T-box transcription factor 3a |
| Gene symbol | tbx3a |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRDPVIQGSS MAYHPFLPHR GPEFAMSAML GHQPPFFPAL ALPPNGSLSL PGALGKPIME 60 QLMGAAETGL HFSSLGHQAA HLRPLKTLEP EEEVEDDPKV HLEAKELWEL FHKRGTEMVI 120 TKSGRRMFPP FKVRCTGLDK KAKYILLMDI VAADDCRYKF HNSRWMVAGK ADPEMPKRMY 180 IHPDSPATGE QWMSKVVNFH KLKLTNNISD KHGFTILNSM HKYQPRFHIV RANDILKLPY 240 STFRTYVFPE TDFIAVTAYQ NDKITQLKID HNPFAKGFRD TGNGRREKRK QLALQSMRSY 300 EEQQKKENGT SDDSSGEQAS FKCFRQASSP AVSTAGHNHL KDFCDSDEDS DEEDKDANAK 360 EGPDSSKIST TTEDSKDQDA GLGKSVFGES DSSSGRRSEK TRADSRSPIT LISSTTRSGE 420 ELKSPVREPA KTTDDCRTVS KENYMPLTVQ TDGAAHLNQN HLHNFGFPPG LAGQQFFNHL 480 GGAHPFLLHP SQFNMGGAFS NMAAGMGPIL AAVSSGGVGS LDGSSLPSPS QSLTGAPMPF 540 HLQQHVLASQ GLAMSPFGGL FPYPYTYMAA AAAASSAASS SVHRHPFLSA VRPRLRYSPY 600 SLPSVPDSTL LTTAMQPMAS SGLEVKGDGM NTSPASAALD SEVTSRSSGS VSLSPKTCTE 660 KDSSSELQSI QRLVSGLEPK PDRARSVSP 689 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TBX3 | 102185207 | A0A452EBG9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | TBX3 | 6926 | O15119 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Tbx3 | 21386 | P70324 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | TBX3 | 740308 | A0A2I3T7H8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Tbx3 | 353305 | Q7TST9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | tbx3a | 556870 | B8JKS6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0003205 | cardiac chamber development |
| GO:0001708 | cell fate specification |
| GO:0007417 | central nervous system development |
| GO:0035050 | embryonic heart tube development |
| GO:0001947 | heart looping |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:0006357 | regulation of transcription by RNA polymerase II |