Gene: Kif20b

Basic information

Tag Content
Uniprot ID D3ZX13
Entrez ID 309523
Genbank protein ID
Genbank nucleotide ID NM_001107609.2
Ensembl protein ID ENSRNOP00000051636
Ensembl nucleotide ID ENSRNOG00000018929
Gene name Kinesin family member 20B
Gene symbol Kif20b
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MESHLNQDGV PRPSYVFSAD PIARPSEINF DGVKLDLSHE FSLVAANPGA NSLESKNYLQ 60
VCLRIRPFTQ SEKGHEAEGC VQVLDSQTVL LKDPQSILGH LSEKSSGQMA QKFSFSRVFG 120
PETSQKEFFQ GCIMQPVKDL LKGHSRLIFT YGLTNSGKTY TFQGTEENIG ILPRTLNVLF 180
DSLQERLYTK MSFKPHRCRE YLQLSSDQEK EESANKNTLL RQIKEVTIHN DSYDILCGRL 240
TNSLTIPEFE ETMNNCEQSS LNVDNIKYSV WVSFFEIYNE SIYDLFVPVS SKLQKRKMLR 300
LSQDVKGYSF IKDLQWIQVS DSKEAYRLLK LGVKHQSVAF TKLNNASSRS HSIFTIRILQ 360
IEDSEIPRVT RVSELSLCDL AGSERSMKTQ SEGERLREAG NINTSLLTLG KCISVLKNSD 420
KSKIQQHVPF RESKLTHYFQ SFFTGKGKIC MIINISQCCS AYDETLNVLK FSTVAQKVYV 480
PDTLSSSQEK SFGSTKSLQD VSLGSNLDNK ILNVKRKTVS WENSLEDVVE NEDLVEDLEE 540
NEETQNMETE LTDEDSDKPL EEGGVCAGHG KNKKLLDLIE NLKKRLINEK KEKLTLEFKI 600
REEVTQEFTQ YWSQREADFK ETLLHEREIL EENAERRLAI FKDLVGKPGE SQDEPASRFC 660
TMELETEEAI ACLQLKYNQV KAELAETKEE LIKAQEELKN KESDSLVQAL KTSSKSLLTS 720
GQIVTKLVSV LGGEGGRINN IQDIKQENTV TCKVDTSLIS NKSTGNETTE MPKKSRTQTH 780
SERKRLNEDG LQLGEPPAKK GLILISPPIT EDQDKREEMQ QSVSEGAEED SRVLQEKNEE 840
LKRLLTIGEN ELRNAKEEKA ELNKQVVSLQ QQLCFFEEKN SSLRAEVEQI QASYDLAAAE 900
LHTQRAVNQE QKDRILQLSG KMETAARRIE SNVSQIKQMQ TKIDELRSLD SPSHISKIDL 960
LNLQDLSSGA NLLNTSQQLP GSDLPSTWVK EFHTQELSRE SSFHSSIEAI WEECKEIVKA 1020
SSKKSHQIQG LEELIEKLQV EVKNCRDENS ELRAKESEDK NRDQQLKEKE SLIQQLREEL 1080
QETTVSLRVQ VQLVAEREQA LSELSRDVTC YKAKVKDLEV MVETQKEECK RLAELEQSIL 1140
EKESAILKLE ASLKELEAKH QDHIRSTTHL NAEEVKFREE ITQLANNLHD TKQLLQSKEE 1200
ENEISRQETE KLKEELAANS VLTQNLQADL QRKEEDCAEL KEKFTDAKKQ IEQVQREVSV 1260
MRDEEKSLRT KINELEKKKN QYSQEIDMKQ RTIQQLKEQL SNQKMEEVVQ QYEKVCKDLS 1320
VKEKLIEAMR LTLVEQEQTQ AEQDRMLEAK SQEADWLAGE LDTWKDKFKD LETRSNQKVT 1380
TEAMEDSDVL SEKFRKLQDE LQESEEKHKA DRKKWLEEKA VLTTQAKEAE TLRNREMKKY 1440
AEDRERCLKL QNEVETLTAQ LAEKTGELQK WREERDQLVT AVETQMQALL SSSKHKDEEI 1500
QQLRKAVAKS TGTENQTMNL KPECNDSVDL GGVETELQST SFEISRNTAE DGSVVLDSCE 1560
VSTENVQSTR FPKPELEIQF TPLQPNKVAV KHPGCATPVT IKIPKARKRK SGEVEEDLVK 1620
CENKKNSTPR SNVKFPVSEH RNSSFKKEQK VFLCPSSKKT YSLRSQASTV GANVASKKKE 1680
GTLQKFGDFL QHSPTILQSK AKKIIETMSS PKLSTVEVSK ENVSQPKKAK RKLYRNEISS 1740
PINISGQVIL MEQKAKETDH QILKRRLRTR TAK 1773

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologKIF20BA0A452EC51Capra hircusPredictionMore>>
1:1 orthologKIF20B9585Q96Q89Homo sapiensPredictionMore>>
1:1 orthologKif20b240641Q80WE4CPOMus musculusPublicationMore>>
1:1 orthologKIF20B450592H2R321Pan troglodytesPredictionMore>>
1:1 ortholog100155885A0A480ZX77Sus scrofaPredictionMore>>
1:1 orthologKIF20B100339334G1SHM7Oryctolagus cuniculusPredictionMore>>
1:1 orthologKif20b309523D3ZX13Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005813 centrosome
GO:0070938 contractile ring
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0045171 intercellular bridge
GO:0005871 kinesin complex
GO:0005874 microtubule
GO:0015630 microtubule cytoskeleton
GO:0030496 midbody
GO:1990023 mitotic spindle midzone
GO:0097431 mitotic spindle pole
GO:0005730 nucleolus
GO:0005654 nucleoplasm
GO:0005634 nucleus
GO:0048471 perinuclear region of cytoplasm
GO:0051233 spindle midzone
GO:0005524 ATP binding
GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed
GO:0016887 ATPase activity
GO:0008017 microtubule binding
GO:0003777 microtubule motor activity
GO:0042803 protein homodimerization activity
GO:0050699 WW domain binding
GO:0007018 microtubule-based movement
GO:0001843 neural tube closure
GO:0048812 neuron projection morphogenesis
GO:0008284 positive regulation of cell population proliferation
GO:0032467 positive regulation of cytokinesis
GO:0090316 positive regulation of intracellular protein transport
GO:1903438 positive regulation of mitotic cytokinetic process
GO:2001224 positive regulation of neuron migration
GO:0035372 protein localization to microtubule
GO:2000114 regulation of establishment of cell polarity
GO:0070201 regulation of establishment of protein localization
GO:0007088 regulation of mitotic nuclear division
GO:2001222 regulation of neuron migration

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0067 ATP-binding
KW-0175 Coiled coil
KW-0505 Motor protein
KW-0547 Nucleotide-binding
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR028828 KIF20B
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase

PROSITE

PROSITE ID PROSITE Term
PS00411 KINESIN_MOTOR_1
PS50067 KINESIN_MOTOR_2

Pfam

Pfam ID Pfam Term
PF00225 Kinesin