Gene: KIF20B

Basic information

Tag Content
Uniprot ID G1SHM7
Entrez ID 100339334
Genbank protein ID
Genbank nucleotide ID XM_008270182.2
Ensembl protein ID ENSOCUP00000002139
Ensembl nucleotide ID ENSOCUG00000002468
Gene name Kinesin family member 20B
Gene symbol KIF20B
Organism Oryctolagus cuniculus
NCBI taxa ID 9986
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MESNLNQDGM PRPSYVFSAD PIARPSEINF DGIKLDLSHE FSLVASKTEV NSLESKDYLQ 60
VCLRIRPFTQ SEKEHESEGC VHILDSQTVL LKDPQSILGR LSEKSSGQLA QKFSFSKVFG 120
PETTQKEFFQ GCVMQPVKDL LKGQSRLIFT YGLTNSGKTY TFRGTEENIG ILPRTLNVLF 180
ANLQEKLYTK MNLKPHRSRE YLRLSPDQEK EEVMTKSALL RQIKEVVMHN DSCDTLYGSF 240
TNSLNIPELE ESLKDCEQSS LNMDNNIKFS VWVSFFEIYN ECIYDLFVPV SSKFQKRKML 300
RLSQDVKGYS FIKDLQWIQV SDSKEAYRLL KLGIKHQSVA FTKLNNASSR SHSIFTIRIL 360
HIEDSEMSRV IGVSELSLCD LAGSERSVKT QNEGERLRET GNINTSLLTL GKCINVLKNS 420
EKSKFQQHVP FRESKLTHYF QSFFNGKGKI CMIVNISQCC FAYDETLNVL KFSAIAQKVY 480
VPDTLNSSQE KFCGTAKSSQ EISLDSNSDN KILNVKRATI SWENNLEDLI EDEDLVQDLE 540
EAEENQNTET EFIDEDMDKT EEAKTLFNHK ENRKLLDLIE DLKKKLINEK KEKLTLEFKI 600
REEVTQEFTQ YWAQREADFK ETLLQEREIL EENAECRLAI FKDLVGKCDI QEEPTSGVCA 660
MKVETEEAIA CLQLKLSQIK AELDKTKEEL IKTKEELKKR DDESDSFVQG LKKSSKVDTS 720
LINNKLTSDE TVEVPKDGKT KTYSERKRLS DYELQQDEPP AKKGLTPTSS AITEQKKSEM 780
QHSSPENRKD ITVLQDNERL KTLLLVEDEL KNEKEEKTEL NKQIVNLQQE LSLSEKKSLM 840
LSIEVQKIQS DYDSAIAELH VLRGINQEQE EKIMKLSKEI ETATRNITNN VSKIKLMQTK 900
IDELRSFDSV SQISNIDLLH LKDLSNDSQE ENLANTQVYQ LDSDYLKSNH VKDYCVQEFS 960
RDNSFHTSIE AIWEECKEIV RASSKKSHQI QELEKQIEKL KTEVESYKDE SHRLEIKECD 1020
IKHQGDLLKE KESIIQQLKE ELQEKNDHLA DQEQRVVEGK RALSELTQDI TRYQEKIKEL 1080
ETVLETQKDE CKHSAKLEQD ILEKESIILK LEGNLKEFQA DLQDSLKNTK DLSEKEVKLK 1140
EEIVQLTNNL QDMTHSLHLM EEEKEANRQE TKKLKEELCA SSALTQSLKA DLQRKEEDYA 1200
ELKEKLTDAK KQIEQVQKEV SVMRDEEKLL RVKINELEKK KNQCSQEIDM KQRTIQQLKE 1260
QLSNQKVDEV IQQYERVCKD LNVKEKIIEG MRLTLEEQEQ TQVEQDQVLE AKLEEADWLA 1320
TELKRWKEKC KEMETKCNQS SNKDLEDSDV LHKKLSKLQD ELQETEQKYK ADRNKWLEEK 1380
TLLISQAKEA ESLRNKEMKK YAEDRERCLK QQNEVEILTA QLGEKNNDLQ KWREERDQLV 1440
AALEIQLKTL ISSNKQKDYE IEQLKEITSE VSKTIKTEVM DIKPTQNSSV DASKVETEPQ 1500
SANFEISGTA VEDGSVVLDS CEVSTENDQS TRFPKPELEI HFTPLRPNQM AVKHSGCTTP 1560
VTVKISKARK RKSNEMEESS IFSSCWKSRN SIIHTPEALC QALVKCENKK NATPRSNLEF 1620
PVSEHRNSSI KKEQKVCTRQ SSKKTYSLRS QASTISINLA TKKKEGTLQK FGDFLQHSPT 1680
ILQSKAKKII ETMSSSKLSS VEASKENVSR PKRAKRKLYT NEISSPLDIS GQVILMDQKV 1740
KESDHQILKR RLRAKTAK 1758

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologKIF20BA0A452EC51Capra hircusPredictionMore>>
1:1 orthologKIF20B9585Q96Q89Homo sapiensPredictionMore>>
1:1 orthologKif20b240641Q80WE4CPOMus musculusPublicationMore>>
1:1 orthologKIF20B450592H2R321Pan troglodytesPredictionMore>>
1:1 ortholog100155885A0A480ZX77Sus scrofaPredictionMore>>
1:1 orthologKIF20B100339334G1SHM7Oryctolagus cuniculusPredictionMore>>
1:1 orthologKif20b309523D3ZX13Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005813 centrosome
GO:0070938 contractile ring
GO:0005829 cytosol
GO:0045171 intercellular bridge
GO:0030496 midbody
GO:1990023 mitotic spindle midzone
GO:0097431 mitotic spindle pole
GO:0005730 nucleolus
GO:0005654 nucleoplasm
GO:0005524 ATP binding
GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed
GO:0008017 microtubule binding
GO:0042803 protein homodimerization activity
GO:0050699 WW domain binding
GO:0007018 microtubule-based movement
GO:0008284 positive regulation of cell population proliferation
GO:0032467 positive regulation of cytokinesis
GO:0007088 regulation of mitotic nuclear division

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0067 ATP-binding
KW-0175 Coiled coil
KW-0505 Motor protein
KW-0547 Nucleotide-binding
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR028828 KIF20B
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase

PROSITE

PROSITE ID PROSITE Term
PS00411 KINESIN_MOTOR_1
PS50067 KINESIN_MOTOR_2

Pfam

Pfam ID Pfam Term
PF00225 Kinesin