| Tag | Content |
|---|---|
| Uniprot ID | H2R321 |
| Entrez ID | 450592 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_016918834.1 |
| Ensembl protein ID | ENSPTRP00000044771 |
| Ensembl nucleotide ID | ENSPTRG00000022813 |
| Gene name | Kinesin family member 20B |
| Gene symbol | KIF20B |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MESNFNQEGV PRPSYVFSAD PIARPSEINF DGIKLDLSHE FSLVAPNTEA NSFESKDYLQ 60 VCLRIRPFTQ SEKELESEGC VHILDSQTVV LKEPQCILGR LSEKSSGQMA QKFSFSKVFG 120 PATTQKEFFQ GCIMQPVKDL LEGQSRLIFT YGLTNSGKTY TFQGTEENIG ILPRTLNVLF 180 DSLQDRLYTK MNLKPHRSRE YLRLSSEQEK EEIASKSALL RQIKEVTVRN DSDDTLYGSL 240 TNSLNISEFE ESIKDYEQAN LNMANSIKFS VWVSFFEIYN EYIYDLFVPV SSKFQKRKML 300 RLSQDVKGYS FIKDLQWIQV SDSKEAYRLL KLGIKHQSVA FTKLNNASSR SHSIFTVKIL 360 QIEDSEMSRV IRVSELSLCD LAGSERTMKT QNEGERLRET GNINTSLLTL GKCINVLKNS 420 EKSKFQQHVP FRESKLTHYF QSFFNGKGKI CMIVNISQCY LAYDETLNVL KFSAIAQKVC 480 VPDTLNSSQE KLFGPVKSSQ DVSLDSNSNS KILNVKRATI SWENSLEDLM EDEDLVEELE 540 NTEETQNVET KLLDEDLDKT LEENKAFISH EEKRKLLDLI EDLKKKLINE KKEKLTLEFK 600 IREEVTQEFT QYWAQREADF KETLLQEREI LEENAERRLA IFKDLVGKCD TREEPAKDIC 660 ATKVETEETH NYVGFEDIID SLQDNVADIK KQAEIAHLYI ASLPDPQEAT ACLELKFNQI 720 KAELAKTKGE LIKTKEELKK REDESDSLIQ ELETSNKKII TQNQRIKELI NIIDQKEDTI 780 NEFQNLKSHM ENTFKCNDKA DTSSLIINNK LICNETVEVP KDSKTKICSE RKRVNENELQ 840 QDEPPAKKGS IHVSSAITED QKKSEEVRPN IAEIEDIRVL QENNEGLRAF LLTIENELKN 900 EKEEKAELNK QIVRFQQELS LSEKKNLTLS KEVQQIQSNY DIAIAELHVQ KSKNQEQEEK 960 IMKLSNEIET ATRSITNNVS QIKLMHTKID ELRTLDSVSQ ISNIDLLNLR DLSNGSEEDN 1020 LPNTQLHLLG NDYLVSKQVK EYRIQEPNRE NSFHSSIEAI WEECKEIVKA SSKKSHQIEE 1080 LEQQIEKLQA EVKGYKDENN RLKVKEKEHK NQDDLLKEKE TPIQQLKEEL QEKNVTLDVQ 1140 IQHVVEGKRA LSELTQGVTC YKAKIKELET ILETQKVERS HSAKLEQDIL EKESIILKLE 1200 RNLKEFQEHL QDSVKNTKDL SVKELKLKEE ITQLTNNLQD MKHLLQLKEE EEETNRQETE 1260 KLKEELSASS ARTQNLKADL QRKEEDYADL KEKLTDAKKQ IEQVQKEVSV MRDEDKLLRI 1320 KINELEKKKN QCSQELDMKQ RTIQQLKEQL NNQKVEEAIQ QYERACKDLN VKEKIIEDMR 1380 MTLEEQEQTQ VEQDQVLEAK LEEVERLATE LEKWKEKCND LETKNNQRSN KEHENNTDVL 1440 GKLTNLQDEL QESEQKYNAD RKKWLEEKMM LITQAKEAEN IRNKEMKKYA EDRERFFKQQ 1500 NEMEILTAQL TEKDSDLQKW REERDQLVAA LEIQLKALIS SNVQKDNEIE QLKRIISETS 1560 KIETQIMDIK PKRISSADPD KLQTEPLSTS FEISRNKVED GSVVLDSCEV STENDQSTRF 1620 PKPELEIQFT PLQPNKMAVK HPGCTTPVTV KIPKARKRKS NEMEEDLVKC ENKKNATPRT 1680 NVKFPISDDR NSSVKKEQKV AIRPSSKKTY SLRSQASIIG VNLATKKKEG TLQKFGDFLQ 1740 HSPSILQSKA KKIIETMSSS KLSNVEASKE NVSQPKRAKR KLYTSEISSP IDISGQVILM 1800 DQKMKESDHQ IIKRRLRTKT AK 1822 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | KIF20B | A0A452EC51 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | KIF20B | 9585 | Q96Q89 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Kif20b | 240641 | Q80WE4 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | KIF20B | 450592 | H2R321 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | 100155885 | A0A480ZX77 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | KIF20B | 100339334 | G1SHM7 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Kif20b | 309523 | D3ZX13 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005813 | centrosome |
| GO:0070938 | contractile ring |
| GO:0005829 | cytosol |
| GO:0045171 | intercellular bridge |
| GO:0005871 | kinesin complex |
| GO:0005874 | microtubule |
| GO:0030496 | midbody |
| GO:1990023 | mitotic spindle midzone |
| GO:0097431 | mitotic spindle pole |
| GO:0005730 | nucleolus |
| GO:0005654 | nucleoplasm |
| GO:0005634 | nucleus |
| GO:0048471 | perinuclear region of cytoplasm |
| GO:0005524 | ATP binding |
| GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed |
| GO:0016887 | ATPase activity |
| GO:0008017 | microtubule binding |
| GO:0003777 | microtubule motor activity |
| GO:0042803 | protein homodimerization activity |
| GO:0050699 | WW domain binding |
| GO:0007018 | microtubule-based movement |
| GO:0001843 | neural tube closure |
| GO:0048812 | neuron projection morphogenesis |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:0090316 | positive regulation of intracellular protein transport |
| GO:1903438 | positive regulation of mitotic cytokinetic process |
| GO:2001224 | positive regulation of neuron migration |
| GO:0035372 | protein localization to microtubule |
| GO:2000114 | regulation of establishment of cell polarity |
| GO:0007088 | regulation of mitotic nuclear division |
| Pfam ID | Pfam Term |
|---|---|
| PF00225 | Kinesin |