Gene: RDH10

Basic information

Tag Content
Uniprot ID E2R0Q8
Entrez ID 486998
Genbank protein ID
Genbank nucleotide ID XM_844782.4
Ensembl protein ID ENSCAFP00000011875
Ensembl nucleotide ID ENSCAFG00000008031
Gene name Retinol dehydrogenase 10
Gene symbol RDH10
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MNIVVEFFVV TFKVLWAFVL AAARWLVRPK EKSVAGQVCL ITGAGSGLGR LFALEFARRR 60
ALLVLWDINT QSNEETAGMV RHIYRDLEAA DAAALQAGNG EEEILPHCNL QVFTYTCDVG 120
KRENVYLTAE RVRKEVGEVS VLVNNAGVVS GHHLLECPDE LIERTMMVNC HAHFWTTKAF 180
LPTMLEINHG HIVTVASSLG LFSTAGVEDY CASKFGVVGF HESLSHELKA AEKDGIKTTL 240
VCPYLVDTGM FRGCRIRKEI EPFLPPLKPD YCVKQAMKAI LTDQPMICTP RLMYIVTFMK 300
SILPFEAVVC MYRFLGADKC MYPFIAQRKQ ATNNNEAKNG I 341

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologRDH10282852Q8HZT6Bos taurusPredictionMore>>
1:1 orthologRDH10486998E2R0Q8Canis lupus familiarisPredictionMore>>
1:1 orthologRDH10102180778A0A452EW84Capra hircusPredictionMore>>
1:1 orthologRDH10157506Q8IZV5Homo sapiensPredictionMore>>
1:1 orthologRdh1098711Q8VCH7CPOMus musculusPublicationMore>>
1:1 orthologRDH10472795H2QWA8Pan troglodytesPredictionMore>>
1:1 orthologRDH10A0A286ZUS8Sus scrofaPredictionMore>>
1:1 orthologRDH10100340133G1SV43Oryctolagus cuniculusPredictionMore>>
1:1 orthologRdh10353252Q80ZF7Rattus norvegicusPredictionMore>>
1:1 orthologrdh10aF1RES0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016021 integral component of membrane
GO:0005811 lipid droplet
GO:0052650 NADP-retinol dehydrogenase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0002138 retinoic acid biosynthetic process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR036291 NAD(P)-bd_dom_sf
IPR032970 RDH10
IPR020904 Sc_DH/Rdtase_CS
IPR002347 SDR_fam

PROSITE

PROSITE ID PROSITE Term
PS00061 ADH_SHORT

Pfam

Pfam ID Pfam Term
PF00106 adh_short