Gene: rdh10a

Basic information

Tag Content
Uniprot ID F1RES0
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSDARP00000066702
Ensembl nucleotide ID ENSDARG00000058730
Gene name NADP-retinol dehydrogenase
Gene symbol rdh10a
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MNIFVEFFLV MLKVCWAIVM AGFKWLIRPK EKSVAGQVCV ITGAGGGLGR LFAKEFARRR 60
ATLVLWDINS HSNEETAEMV RQIYREQDNP MSKEGAVGGV EEVPPFQPQV YTYVLDVGKR 120
ESVYSTAEKV RKEVGEVDLL INNAGVVSGH HLLECPDELI ERTMVVNCHA HFWTTKAFLP 180
KMLEMNHGHI VTVASSLGLF STAGVEDYCA SKFGAIGFHE SLSHEIQASE KDGIKMTLVC 240
PYLVDTGMFR GCRIRKEIEP FLPPLRPEFC VKQAMRAILT DQPMICTPRI VYMVNFMKSI 300
LPFEAIVCMY RFLGADKCMY PFLAQRKEAM NNNEAKNGI 339

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologRDH10282852Q8HZT6Bos taurusPredictionMore>>
1:1 orthologRDH10486998E2R0Q8Canis lupus familiarisPredictionMore>>
1:1 orthologRDH10102180778A0A452EW84Capra hircusPredictionMore>>
1:1 orthologRDH10157506Q8IZV5Homo sapiensPredictionMore>>
1:1 orthologRdh1098711Q8VCH7CPOMus musculusPublicationMore>>
1:1 orthologRDH10472795H2QWA8Pan troglodytesPredictionMore>>
1:1 orthologRDH10A0A286ZUS8Sus scrofaPredictionMore>>
1:1 orthologRDH10100340133G1SV43Oryctolagus cuniculusPredictionMore>>
1:1 orthologRdh10353252Q80ZF7Rattus norvegicusPredictionMore>>
1:1 orthologrdh10aF1RES0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0052650 NADP-retinol dehydrogenase activity
GO:0002138 retinoic acid biosynthetic process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0256 Endoplasmic reticulum
KW-0472 Membrane
KW-0492 Microsome
KW-0560 Oxidoreductase
KW-1185 Reference proteome
KW-0735 Signal-anchor
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR036291 NAD(P)-bd_dom_sf
IPR032970 RDH10
IPR020904 Sc_DH/Rdtase_CS
IPR002347 SDR_fam

PROSITE

PROSITE ID PROSITE Term
PS00061 ADH_SHORT

Pfam

Pfam ID Pfam Term
PF00106 adh_short