| Tag | Content |
|---|---|
| Uniprot ID | Q8IZV5 |
| Entrez ID | 157506 |
| Genbank protein ID | AAQ88637.1; AAN64747.1; AAH67131.1; |
| Genbank nucleotide ID | NM_172037.4 |
| Ensembl protein ID | ENSP00000240285 |
| Ensembl nucleotide ID | ENSG00000121039 |
| Gene name | Retinol dehydrogenase 10 |
| Gene symbol | RDH10 |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol. |
| Sequence | MNIVVEFFVV TFKVLWAFVL AAARWLVRPK EKSVAGQVCL ITGAGSGLGR LFALEFARRR 60 ALLVLWDINT QSNEETAGMV RHIYRDLEAA DAAALQAGNG EEEILPHCNL QVFTYTCDVG 120 KRENVYLTAE RVRKEVGEVS VLVNNAGVVS GHHLLECPDE LIERTMMVNC HAHFWTTKAF 180 LPTMLEINHG HIVTVASSLG LFSTAGVEDY CASKFGVVGF HESLSHELKA AEKDGIKTTL 240 VCPYLVDTGM FRGCRIRKEI EPFLPPLKPD YCVKQAMKAI LTDQPMICTP RLMYIVTFMK 300 SILPFEAVVC MYRFLGADKC MYPFIAQRKQ ATNNNEAKNG I 341 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.