Tag | Content |
---|---|
Uniprot ID | E2RF25 |
Entrez ID | 483013 |
Genbank protein ID | |
Genbank nucleotide ID | XM_540128.5 |
Ensembl protein ID | ENSCAFP00000007617 |
Ensembl nucleotide ID | ENSCAFG00000005048 |
Gene name | Intraflagellar transport 172 |
Gene symbol | IFT172 |
Organism | Canis lupus familiaris |
NCBI taxa ID | 9615 |
Cleft type | |
Developmental stage | |
Data sources | Homology search |
Reference | |
Functional description | |
Sequence | MQLKHLRTLL SPQDGAAKVT CMAWSHNNAK FAVCTVDRVV LLYDEHGERR DKFSTKPADM 60 KYGRKSYMVK GMAFSPDSTK IAIGQTDNII YVYKIGEDWG DKKVICNKFI QTSAVTCLQW 120 PAEHIIVFGL AEGKVRLANT KTNKSSTIYG TDSYVVSLTT NCSGKGILSG HADGTIVRYF 180 FDDEGSGESQ GKLVNHPCPP YALAWATNSI VAAGCDRRIV AYGKEGHVLQ TFDYSRDPNE 240 REFTTAAASP GGQSVVLGSY DRLRVLNWSP RRSVWEEAKP KEIANLYTVT ALAWKRDGSR 300 LCAGTLCGGV EQFDCCLRRS IYKNKFELTY VGPSQVIVKN LSSGTRVVLK SHYGYEVEEV 360 KILGKERYLV AHTSDTLLLG DLNTNRLSEV AWQGSGGNEK YFFENENVCM IFNAGELTLV 420 EYGSNDTLGS VRTEFMNPHL ISVRINERRQ RGMEDNKKLA YLVDIKTIAI VDLIGGYNIG 480 TISHDSRVDW LELNETGHKL LFRDRKLRLH LYDIESCTKT MILNFCSYVQ WVPGSDVLVA 540 QNRNSLCVWY NIEAPERVTM SSIRGDVIGL ERGGGKTEVM VTEGVTTVAY TLDEGLIEFG 600 TAIDDGNYTR ATAFLETLEM TPETEAMWKT LSKLALEARQ LHIAERCFSA LGHVAKARFL 660 HETNEIADQV SREYGGEGTD FYQVRARLAM LEKNYKLAEM IFLEQNAVEE AMDMYQELHR 720 WDECIAVAQA KGHPALEKLR RGYYQWLMDT QQEERAGELQ ESQGDGLAAI SLYLKAGLPA 780 KAARLVLARE ELLANTELVE HITAALVKGE LYERAGDLFE KIQNPQRALE CYCKGNAFMK 840 AVELARLAFP VEVVRLEEAW GDHLVQQKQL DAAINHYIEA RCSIKAIEAA LGARQWKKAI 900 YILDLQDQNT ASKYYPRVAQ HYASLQEYEI AEELYIKGDQ TKDAIDMYTQ AGRWEQAHKL 960 AVKCMRPEDV SVLYITQAQE MEKQGKYREA ERLYVTVEEP DLAITMFKKH KLYEDMIRLV 1020 GKHHPDLLSD THLHLGKELE AEGRLQEAEY HYLEAQEWKA TVNMYRSSGL WEEAYRVAKA 1080 HGEANAHKHV AYLWAKSLGG ESAVRLLNKL GLLEAAIDHA ADNCSFEFAF ELSRLALKHK 1140 TPEIHLRYAM YLEDEGKFEE AEAEFIRAGK PKEAVLMFFH NQDWEAAQRV AEAHDPDSVA 1200 EVLLRQAREA LEEKDFQKAE GLLLRAQRPG LALNYYKEAG LWSDALRICK DYVPGQLEAL 1260 QEEYEREATK KGARGLEGLV EQARQWEQAG EYGRAVDCYL KVRDSSSGSL MEKCWMKAAE 1320 LAIKFLPPQR SLEVVQAVGP QLIGIGKHSA AAELYLNLDL VKEAIDAFIE GEEWNKAKRV 1380 AKELDPRYED YVDQHYKEFL KNQGKVDSLV GVDVVAALDL YVEQGQWDKC IETATKQNYK 1440 ILHKYVALYA THLIREGGYG QALALYVQHG APANPQNFNI YKRIFTDMVS SPGTNSAEAY 1500 HNWADLRDVL FNLCENLVKS SEVNTPAHEE FETMLLIAHY YATRSAAQSV KQLETVAARL 1560 SVSLLRHTQL LPADKAFYEA GIAAKAVGWE NMAFIFLNRF LDLTDAIEEG TLDALDHSDF 1620 QDTDIPFEVP LPAKQHVPEA QREEVRDWVL TVSMDQRLEQ VLPRDERGAY EASLVAVSTG 1680 VRALPCLITG YPILRNKIEF KRPGKAANKD NWNKFLMAIK TSHSPVCQDV LKFISQWCGG 1740 LPSTSFSFQ 1749 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
---|---|---|---|---|---|---|---|---|
1:1 ortholog | IFT172 | 483013 | E2RF25 | Canis lupus familiaris | Prediction | More>> | ||
1:1 ortholog | IFT172 | A0A452EH68 | Capra hircus | Prediction | More>> | |||
1:1 ortholog | IFT172 | 26160 | Q9UG01 | Homo sapiens | Prediction | More>> | ||
1:1 ortholog | Ift172 | 67661 | Q6VH22 | CPO | Mus musculus | Publication | More>> | |
1:1 ortholog | IFT172 | 459104 | K7B8Z3 | Pan troglodytes | Prediction | More>> | ||
1:1 ortholog | IFT172 | 100348467 | G1SLK9 | Oryctolagus cuniculus | Prediction | More>> | ||
1:1 ortholog | ift172 | 432389 | Q5RHH4 | Danio rerio | Prediction | More>> |
GO ID | GO Term |
---|---|
GO:0005930 | axoneme |
GO:0036064 | ciliary basal body |
GO:0030992 | intraciliary transport particle B |
GO:0097598 | sperm cytoplasmic droplet |
GO:0097225 | sperm midpiece |
GO:0097228 | sperm principal piece |
GO:0060348 | bone development |
GO:0007420 | brain development |
GO:0031122 | cytoplasmic microtubule organization |
GO:0009953 | dorsal/ventral pattern formation |
GO:0048596 | embryonic camera-type eye morphogenesis |
GO:0008544 | epidermis development |
GO:0001947 | heart looping |
GO:0061525 | hindgut development |
GO:0042073 | intraciliary transport |
GO:0070986 | left/right axis specification |
GO:0060173 | limb development |
GO:0050680 | negative regulation of epithelial cell proliferation |
GO:0045879 | negative regulation of smoothened signaling pathway |
GO:0001843 | neural tube closure |
GO:1905515 | non-motile cilium assembly |
GO:0007219 | Notch signaling pathway |
GO:0045880 | positive regulation of smoothened signaling pathway |
GO:0016485 | protein processing |
GO:0060021 | roof of mouth development |
GO:0007224 | smoothened signaling pathway |
GO:0021522 | spinal cord motor neuron differentiation |
Pfam ID | Pfam Term |
---|---|
PF00400 | WD40 |