| Tag | Content |
|---|---|
| Uniprot ID | G1SLK9 |
| Entrez ID | 100348467 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_002709949.3 |
| Ensembl protein ID | ENSOCUP00000003749 |
| Ensembl nucleotide ID | ENSOCUG00000004327 |
| Gene name | Intraflagellar transport 172 |
| Gene symbol | IFT172 |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MQLKHLRTLL SPQDGAAKVT CMAWSQNNAK FAVCTVDRVV LLYDEHGERR DKFSTKPADM 60 KYGRKSYMVK GMAFSPDSTK IAIGQTDNII YVYKIGEDWG DKKVICNKFI QTSAVTCLQW 120 PAEYIIVFGL AEGKVRLANT KTNKSSTIYG TDSYVVSLTT NCSGKGILSG HADGTIVRYF 180 FDDEGSGESQ GKLVNHPCPP YALAWATNSI VAAGCDRRIV AYGKEGHVLQ TFDYSRDPQE 240 REFTTAAASP GGQSVVLGSY DRLRVFNWSP RRSIWEEARP KEIANLYTIT ALAWKRDGSR 300 LCTGTLCGGV EQFDCCLRRS IYKNKFELTY VGPSQVIVKN LSSGTRVVLK SHYGYEVEEV 360 KILGKERYLV AHTSDTLLLG DLNTNRLSEV AWQGSGGNEK YFFENENVCM IFNAGELTLV 420 EYGSNDTLGS VRTEFMNPHL ISVRINERCQ RGMEDNKKLA YLVDIKTIAV VDLIGGYNIG 480 TISHESRVDW LELNETGHKL LFRDRKLRLH LYDIESCSKT MILNFCSYVQ WVPGSDVLVA 540 QNRNSLCVWY NIEAPERVTM SSIRGDVVGL ERGGGKTEVM VSEGVTTVAY TLDEGLIEFG 600 TAIDDGNYTR ATAFLETLEM TPETEAMWKT LSKLALKAKQ LHIAERCFSA LGHVAKARFL 660 HETNEIADQV SREYGGEGTD FYQVRARLAM LEKNYKLAEM IFLEQNAIEE AMAMYQELHR 720 WDECIAVAEA KGHPALEKLR RGYYQWLMDT KQEERAGELQ ESQGDGLAAI SLYLKAGLPA 780 KAARLVLTRE ELLANTELVE RITTALTKGE LYERAGDLFE KIRNPQRALE CYCKGNAFVK 840 AVELARLAFP GEVVRLEEAW GDHLVQQKQL DAAINHYIEA RCSIKAIEAA LGARQWKKAI 900 YILDLQDRNI ASKYYPRVAQ HYASLQAYEI AEELYIKGDR TKDAIDMYTQ AGRWEQAHKL 960 AMKCMRPEDV SVLYINQAQE MEKQGKYREA ERLYVTVDEP DLAITMFKKH KLYGDMIRLV 1020 GKHHPDLLSD THLHLGKELE AEGRLQEAEY HYLEAQEWKA TVNMYRSSGL WEEAYQVAKA 1080 HGGANAHKHV AYLWAKSLGG KAAVRLLNKL GLLEAAIDHA ADNCSFEFAF ELSRLAAKHK 1140 TPEIHLRYAM YLEDEGKFEE AEAEFISAGK PKEAVLMFVH NQDWEAAQRV AEAHDPDSVA 1200 EVLVVQARGA LEEKDFQKAE GLLLRAQRPD LALNYYKEAG LWSDALRICK DYMPGQLEAL 1260 QEEYEREATK KGARSVEGLV EQARQWEQAG EYSRAVDCYL KVRESGSSSL QEKCWMKAAE 1320 LAIKFLPPQR SLEVVRAVGP QLIGTGKHSA AAELYLNLDL VKEAIDAFIE GEEWNKAKRV 1380 AKELDPRYED YVDQHYKEFL KNQGKVDSLV GVDVVAALDL YVEQGQWDKC IETATKQNYK 1440 ILHKYVALYA THLIREGGCA QALALYVQHG APANPQNFNI YRRIFADVVS SPGTNCAEAY 1500 HSWADLRDVL FNLCENLVKS SEANSPAHEE FETMLLIAHY YATRSAAQSV KQLETVAARL 1560 SVSLLRHTQL LPADKAFYEA GTAAKAVGWE NMAFIFLNRF LDLTDAIEEG TLDALDHSDF 1620 QDTDIPFEVP LPAKQHVPEA QREEVRDWVL TVSMDQRLEQ VLPRDERGAY EASLVAANTG 1680 VRALPCLITG YPILRNKIEF KRPGKAANKD NWNKFLMAIK TSHSPVCQDV LKFISQWCGG 1740 LPSTSFSFQ 1749 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | IFT172 | 483013 | E2RF25 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | IFT172 | A0A452EH68 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | IFT172 | 26160 | Q9UG01 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ift172 | 67661 | Q6VH22 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | IFT172 | 459104 | K7B8Z3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | IFT172 | 100348467 | G1SLK9 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | ift172 | 432389 | Q5RHH4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0030992 | intraciliary transport particle B |
| GO:0097598 | sperm cytoplasmic droplet |
| GO:0097225 | sperm midpiece |
| GO:0097228 | sperm principal piece |
| GO:0060348 | bone development |
| GO:0007420 | brain development |
| GO:0031122 | cytoplasmic microtubule organization |
| GO:0009953 | dorsal/ventral pattern formation |
| GO:0048596 | embryonic camera-type eye morphogenesis |
| GO:0008544 | epidermis development |
| GO:0001947 | heart looping |
| GO:0061525 | hindgut development |
| GO:0070986 | left/right axis specification |
| GO:0060173 | limb development |
| GO:0050680 | negative regulation of epithelial cell proliferation |
| GO:0045879 | negative regulation of smoothened signaling pathway |
| GO:0001843 | neural tube closure |
| GO:1905515 | non-motile cilium assembly |
| GO:0007219 | Notch signaling pathway |
| GO:0045880 | positive regulation of smoothened signaling pathway |
| GO:0016485 | protein processing |
| GO:0060021 | roof of mouth development |
| GO:0007224 | smoothened signaling pathway |
| GO:0021522 | spinal cord motor neuron differentiation |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| Pfam ID | Pfam Term |
|---|---|
| PF00400 | WD40 |