| Tag | Content |
|---|---|
| Uniprot ID | Q5RHH4; Q6IVW1; |
| Entrez ID | 432389 |
| Genbank protein ID | CAI20958.1; AAT39119.1; |
| Genbank nucleotide ID | NM_001002312.1 |
| Ensembl protein ID | ENSDARP00000061333 |
| Ensembl nucleotide ID | ENSDARG00000041870 |
| Gene name | Intraflagellar transport protein 172 homolog |
| Gene symbol | ift172 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Required for the maintenance and formation of cilia. |
| Sequence | MQLKYMKTLL TPQDGAAKVT CMAWAPNNAK FAVCTIDRVV ILYDEQGEKR DRFTTKPADP 60 KYGKKTYVVK SMAFSPDSTK IAVAQTDNII FVYKIGEEWG DKKVICNKFI QTSAVTSLVW 120 PSEHAIIFGL AEGKVRQANT KTSKSSTIYG TDSYVVSLTS NVSGKGILSG HADGTVVRYF 180 IDDEGSGESQ GKLLTHACPP YALAWGTNSI IVAGCDKKIV AYGKEGNVIQ TFDYSRDRAE 240 KEFTVAASSP SGQSIVVGSF DRLRVFNWSP RKGTWDESSP KEIPNLYTIT ALSWKKDGSR 300 LSVGTLCGGV EMFDCCLRRS IYKNKFEMTY VGLSQVIVRN LSTGTRVVLK SQYGYEIDEV 360 KVMGKDQYLV AHTSDTLLLG DLVSNKLSEV AWQGSGGNEK FFFENETVCM IFNAGELALV 420 EYGSNDILGS VRTEFMNPHL ISVRLNERRQ RGVEDNKKLA YLIDIKTIAI VDLVGGYNLG 480 TISHDSKIDW LELNETGRKL LFRDKKLRLH LYDIESSVKS TMLSFCPYVQ WVPGSDVVVA 540 QNRGNLCVWY TIDSPERVTM FPLKGDIVDL ERSNGKTEVI VNEGVNSISY TLDEGLIEFG 600 TAIDDGDYYR ATAFLETLEM SAETEAMWKT LSKLSLEAQQ LHIAERCFAA LGDVSKARFL 660 NETNKIADAV AKEYDGDGTD HYQVKARLAM LDKNFKLAEM YYMEQNAVDE VMEMYQELHM 720 WDECIAVAEG KGHPELDNLR RSYYSYLMET NQNEKAAEVK ENEGDFTGAV NLYLKAGLPA 780 KAAWLAMSKD ELLSSQDIVS RITAALIKGE FYERAGDLFE RTRNNQRALE CYRKGNAFKK 840 AVDLARVAFP AEVVKLEEVW GDYLVQQKQM DAAINHYIEA GRSIKAIEAA IAARQWKKAL 900 HILELQEDRT AAKYYLKIAQ YYASVQEFEV AERLFVKGDH IKDAIDMYTQ AGRWEQAHKL 960 AVKCMTQEDV SVLYVSRAQE LEKEGKYKEA ERLFTTVDEP DLAITMYKKN KMYDDMIRLV 1020 AVHHKDLLQE THIHLAKELE AESRFQEAEY HYLEGQDWKA AVNMYRVNDM WEEAYRIAKT 1080 HGGANAHKQV AYLWAKSLGG EAAVKLLNKF GLLETAIDFA ADNYTFDFAF ELARLSMKQK 1140 IPDIHLKNAM FLEDQGKFNE AEIEFIKAGK PKEAVLMHVH NKDWSNAQRV AEAHDPESVA 1200 DILVSQAKFC FDQKEFQKAE AFLLRAQRPE LAIKYYKDAG MWTDAMRICK DYLPSKLSVL 1260 QKEYESEGNW GVEGMIEQAQ EWEQTGEYSR AVDCYLKVKD SSNLDLLLKC WMKAAELAIK 1320 FLSHDKAVDV SQIVGPRLIQ LRKYNEAAEL YLNLDLIKNA IDAFIEGEEW NKAKRVAKEL 1380 DPRLEEYVDK RYKEHLKNQG KVDSLVGVDV VAALDMYAER GQWEKCIDTA SKQNFKVLHK 1440 YIALYATHLI KEGEVEKVLS LYIQHGVPAY SQNFNIYKRM FQELVNLRDR DCAEAFRMWS 1500 DLRDVLLLLC ENLTKSSEAN SPAHEEFEQM LLVAHYYATR SAAKGIDQLS SVAAKLSISL 1560 LRHTELIPAD KAFYEAGLAA KAVGWENMAF IFLNRFLDLA DGIDEGTLDA LDHTDFQDTD 1620 IPFEVPVPSR LHVTVEKREE IREWVLTVSM DQRVEQVLPK DERGTYEASL VAASTGIRSL 1680 PCVITGYPVL RNKIEFKRPG MAANKDDWNK FLMATKTTHS PECQDVLKFI TQWCGGLPSA 1740 GYSFH 1745 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | IFT172 | 483013 | E2RF25 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | IFT172 | A0A452EH68 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | IFT172 | 26160 | Q9UG01 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ift172 | 67661 | Q6VH22 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | IFT172 | 459104 | K7B8Z3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | IFT172 | 100348467 | G1SLK9 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | ift172 | 432389 | Q5RHH4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005930 | axoneme |
| GO:0036064 | ciliary basal body |
| GO:0005929 | cilium |
| GO:0030992 | intraciliary transport particle B |
| GO:0060271 | cilium assembly |
| GO:0042073 | intraciliary transport |
| GO:0045494 | photoreceptor cell maintenance |
| GO:0048793 | pronephros development |
| GO:0032006 | regulation of TOR signaling |
| GO:0060041 | retina development in camera-type eye |