Gene: TCN2

Basic information

Tag Content
Uniprot ID E2RFH1
Entrez ID 486355
Genbank protein ID
Genbank nucleotide ID XM_005636448.2
Ensembl protein ID ENSCAFP00000018873
Ensembl nucleotide ID ENSCAFG00000012827
Gene name Transcobalamin 2
Gene symbol TCN2
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MGHLGVLLFL LGGLGTLADI CEIPEVNSKL VETLGQRLLP WIDWLSLEHL NPSIYIGLRL 60
SSLQAGAREA FYLHILKLKY QQSFLSPRLA VNDDNRDDQA KPSMGQLALY LLALRANCEF 120
VGGHKGDRLV SQLKRFLEDE KRAIGPNHKG HPRTSYYQYG LGILALCVHQ KRLHDTVVGK 180
LLYAVEHDHH LHRDHLSVDT VAMAGLAFTC LDDSNFNPSQ RHRITLAIRT VREKILKAQT 240
PEGYFGNVYS TPLALQLLMN SFMPGEKLGT ACLKARTALL ASMKDGAFRN ALLISQLLPV 300
LNGKSYVDLI SPDCEAPRVL LQPAMENPSQ TREVISVMLK VPSVLPPYRH SISVPAGSSL 360
EDVFKKAQEL GGFTYGTQNT LSGPYLTSVM GKEVGEREFW QLLRAPDTPL LEGIAEYTPK 420
NGETIELRLV SW 432

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTCN2281518Q9XSC9Bos taurusPredictionMore>>
1:1 orthologTCN2486355E2RFH1Canis lupus familiarisPredictionMore>>
1:1 orthologTCN2102190723A0A452DSJ0Capra hircusPredictionMore>>
1:1 orthologTCN2100063639F6U5V3Equus caballusPredictionMore>>
1:1 orthologTCN26948P20062Homo sapiensPublicationMore>>
1:1 orthologTcn221452O88968Mus musculusPredictionMore>>
1:1 orthologTCN2470178H2QLH6Pan troglodytesPredictionMore>>
1:1 orthologTCN2100152846F1RPE4Sus scrofaPredictionMore>>
1:1 orthologTcn264365G3V6K1Rattus norvegicusPredictionMore>>
1:1 orthologtcn2407646F2Z4S3Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005615 extracellular space
GO:0031419 cobalamin binding
GO:0015889 cobalamin transport

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR002157 Cbl-bd_prot
IPR027954 DUF4430

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF01122 Cobalamin_bind
PF14478 DUF4430