Gene: Tcn2

Basic information

Tag Content
Uniprot ID G3V6K1
Entrez ID 64365
Genbank protein ID EDM00198.1; EDM00197.1;
Genbank nucleotide ID XM_006251370.3; NM_022534.2; XM_006251367.3; XM_006251368.2; XM_006251366.2; XM_017599370.1;
Ensembl protein ID ENSRNOP00000005934
Ensembl nucleotide ID ENSRNOG00000004280
Gene name Transcobalamin 2, isoform CRA_a
Gene symbol Tcn2
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MELLKALLLL SGVLGALAEF CVIPKMDGQL VEKLGQRLLP WMDRLSSEQL NPSIYVGLRL 60
SSMQAGTKEN LYLHNLKLHY QQCLLRSTSS DDNSGCQTKI SGGSLALYLL ALRANCELLG 120
SRKGDRMVSQ LKWFLEDEKK AIGHHHEGHP HTSYYQYGLS ILALCVHRKR VHDSVVGKLL 180
YAVEHDYFTY QGHLSVDTEA MAGLAFTCLE RFNFNSDLRP RITTAIETVR EKILKAQAPE 240
GYFGNIYSTP LALQMLMTSP GVGLGPACLK ARKSLLLSLQ DGAFQNPMMI SQLLPVLNHK 300
TYLNLISPDC QAPRVMLVPA TEDPVHLSEV SVTLKVSSVL PPYERTVSVF AGASLEDVLK 360
RARDLGEFTY GTQASLSGPY LTSVLGKEAG DREYWQLLRV PDTPLLQGIA DYKPKNGETI 420
ELRLVRW 427

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTCN2281518Q9XSC9Bos taurusPredictionMore>>
1:1 orthologTCN2486355E2RFH1Canis lupus familiarisPredictionMore>>
1:1 orthologTCN2102190723A0A452DSJ0Capra hircusPredictionMore>>
1:1 orthologTCN2100063639F6U5V3Equus caballusPredictionMore>>
1:1 orthologTCN26948P20062Homo sapiensPublicationMore>>
1:1 orthologTcn221452O88968Mus musculusPredictionMore>>
1:1 orthologTCN2470178H2QLH6Pan troglodytesPredictionMore>>
1:1 orthologTCN2100152846F1RPE4Sus scrofaPredictionMore>>
1:1 orthologTcn264365G3V6K1Rattus norvegicusPredictionMore>>
1:1 orthologtcn2407646F2Z4S3Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005615 extracellular space
GO:0031419 cobalamin binding
GO:0015889 cobalamin transport

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR002157 Cbl-bd_prot
IPR027954 DUF4430

PROSITE

PROSITE ID PROSITE Term
PS00468 COBALAMIN_BINDING

Pfam

Pfam ID Pfam Term
PF01122 Cobalamin_bind
PF14478 DUF4430