| Tag | Content |
|---|---|
| Uniprot ID | E2RJY3 |
| Entrez ID | 482313 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_845319.4 |
| Ensembl protein ID | ENSCAFP00000003194 |
| Ensembl nucleotide ID | ENSCAFG00000002191 |
| Gene name | Distal-less homeobox 5 |
| Gene symbol | DLX5 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTGVFDRRVP SIRSGDFQAP FQTSAAMHHP SQESPTLPES SATDPDYYSP TGGAPHGYCS 60 PTSASYGKAL NPYQYQYHGV SGSAGSYPAK AYADYSYASP YHQYGGAYNR VPSAASQPEK 120 EVAEPEVRMV NGKPKKVRKP RTIYSSFQLA ALQRRFQKTQ YLALPERAEL AASLGLTQTQ 180 VKIWFQNKRS KIKKIMKNGE MPPEHSPSSS DPMACNSPQS PAVWEPQGSS RSLSHHPHAH 240 PPTSNQSPAS SYLENSASWY PSAASSINSH LPPPGSLQHP LALASGTLY 289 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | DLX5 | 507415 | Q1RMR7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | DLX5 | 482313 | E2RJY3 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | DLX5 | 102184778 | A0A452DYR1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | DLX5 | 100052263 | F7DY45 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | DLX5 | 1749 | P56178 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Dlx5 | 13395 | P70396 | CPO | E13.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | DLX5 | 463554 | H2QUZ2 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | DLX5 | A0A287AIX4 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | DLX5 | 100008630 | G1SVH5 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Dlx5 | 25431 | A0A0G2JSK6 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | dlx5a | 30569 | Q5XJL9 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0000790 | nuclear chromatin |
| GO:0005634 | nucleus |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0071837 | HMG box domain binding |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0043565 | sequence-specific DNA binding |
| GO:0048646 | anatomical structure formation involved in morphogenesis |
| GO:0030509 | BMP signaling pathway |
| GO:0030154 | cell differentiation |
| GO:0008283 | cell population proliferation |
| GO:0030326 | embryonic limb morphogenesis |
| GO:0001958 | endochondral ossification |
| GO:0030855 | epithelial cell differentiation |
| GO:0060325 | face morphogenesis |
| GO:0042472 | inner ear morphogenesis |
| GO:0097376 | interneuron axon guidance |
| GO:0021889 | olfactory bulb interneuron differentiation |
| GO:0060166 | olfactory pit development |
| GO:0001649 | osteoblast differentiation |
| GO:0090263 | positive regulation of canonical Wnt signaling pathway |
| GO:0050679 | positive regulation of epithelial cell proliferation |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| GO:0060021 | roof of mouth development |