Gene: dlx5a

Basic information

Tag Content
Uniprot ID Q5XJL9
Entrez ID 30569
Genbank protein ID AAH83280.1
Genbank nucleotide ID NM_131306.2
Ensembl protein ID ENSDARP00000100492
Ensembl nucleotide ID ENSDARG00000042296
Gene name Distal-less homeobox gene 5a
Gene symbol dlx5a
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MTGVFDRRIP SIKPADFQNP FQLSTMHHPS QESPTLPEST ATDSGYYSPA GGVHHGYCSP 60
NSGTYGKPLN AYQYQYHGVN GSSGNYSAKS YPDYGSYSTA YHQYAGTYNR VQSQPSPQEK 120
ETAEPEVRMV NGKPKKVRKP RTIYSSFQLA ALQRRFQNTQ YLALPERAEL AASLGLTQTQ 180
VKIWFQNKRS KLKKIMKNGE LPPEHSPSSS DPMACNSPQS PAVWDSQGPQ RPHHQPQNIN 240
TAASTFLESA SSSWYSSTGA MNSHLQAPGT LHSLALGSGT LY 282

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologDLX5507415Q1RMR7Bos taurusPredictionMore>>
1:1 orthologDLX5482313E2RJY3Canis lupus familiarisPredictionMore>>
1:1 orthologDLX5102184778A0A452DYR1Capra hircusPredictionMore>>
1:1 orthologDLX5100052263F7DY45Equus caballusPredictionMore>>
1:1 orthologDLX51749P56178Homo sapiensPredictionMore>>
1:1 orthologDlx513395P70396CPOE13.5Mus musculusPublicationMore>>
1:1 orthologDLX5463554H2QUZ2Pan troglodytesPredictionMore>>
1:1 orthologDLX5A0A287AIX4Sus scrofaPredictionMore>>
1:1 orthologDLX5100008630G1SVH5Oryctolagus cuniculusPredictionMore>>
1:1 orthologDlx525431A0A0G2JSK6Rattus norvegicusPredictionMore>>
1:1 orthologdlx5a30569Q5XJL9Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0003677 DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR022135 Distal-less_N
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
IPR000047 HTH_motif

PROSITE

PROSITE ID PROSITE Term
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2

Pfam

Pfam ID Pfam Term
PF12413 DLL_N
PF00046 Homeodomain