| Tag | Content |
|---|---|
| Uniprot ID | F1M7F5 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000040229 |
| Ensembl nucleotide ID | ENSRNOG00000005708 |
| Gene name | Matrix metalloproteinase-16 |
| Gene symbol | Mmp16 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MILLAFSSGR RLDFVHRSGV FFFQTLLWIL CATVCGTEQY FNVEVWLQKY GYLPPTDPRM 60 SVLRSAETMQ SALAAMQQFY GINMTGKVDR NTIDWMKKPR CGVPDQTRGS SKFNIRRKRY 120 ALTGQKWQHK HITYSIKNVT PKVGDPETRR AIRRAFDVWQ NVTPLTFEEV PYSELENGKR 180 DVDITIIFAS GFHGDSSPFD GEGGFLAHAY FPGPGIGGDT HFDSDEPWTL GNPNHDGNDL 240 FLVAVHELGH ALGLEHSNDP TAIMAPFYQY METDNFKLPN DDLQGIQKIY GPPDKIPPPT 300 RPLPTVPPHR SVPPADPRKN DRPKPPRPPT GRPSYPGAKP NICDGNFNTL AILRREMFVF 360 KDQWFWRVRN NRVMDGYPMQ ITYFWRGLPP SIDAVYENSD GNFVFFKGNK YWVFKDTTLQ 420 PGYPHDLITL GNGIPPHGID SAIWWEDVGK TYFFKGDRYW RYSEEMKTMD PGYPKPITIW 480 KGIPESPQGA FVHKENGFTY FYKGKEYWKF NNQILKVEPG YPRSILKDFM GCDGPTDRDK 540 EGLSPP 546 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MMP16 | 282886 | F1N797 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | MMP16 | 487036 | F1PLV8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | MMP16 | A0A452EG47 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | MMP16 | 4325 | P51512 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Mmp16 | 17389 | Q9WTR0 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | MMP16 | A0A2I3SEA5 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | MMP16 | 100153257 | A0A287AKC1 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | MMP16 | 100101605 | G1T0W4 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Mmp16 | F1M7F5 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0031012 | extracellular matrix |
| GO:0005887 | integral component of plasma membrane |
| GO:0070006 | metalloaminopeptidase activity |
| GO:0004222 | metalloendopeptidase activity |
| GO:0008270 | zinc ion binding |
| GO:0035988 | chondrocyte proliferation |
| GO:0030574 | collagen catabolic process |
| GO:0097094 | craniofacial suture morphogenesis |
| GO:0048701 | embryonic cranial skeleton morphogenesis |
| GO:0001958 | endochondral ossification |
| GO:0016485 | protein processing |
| InterPro ID | InterPro Term |
|---|---|
| IPR000585 | Hemopexin-like_dom |
| IPR036375 | Hemopexin-like_dom_sf |
| IPR018487 | Hemopexin-like_repeat |
| IPR018486 | Hemopexin_CS |
| IPR033739 | M10A_MMP |
| IPR024079 | MetalloPept_cat_dom_sf |
| IPR028697 | MMP16 |
| IPR001818 | Pept_M10_metallopeptidase |
| IPR021190 | Pept_M10A |
| IPR021158 | Pept_M10A_Zn_BS |
| IPR006026 | Peptidase_Metallo |
| IPR002477 | Peptidoglycan-bd-like |
| IPR036365 | PGBD-like_sf |