| Tag | Content |
|---|---|
| Uniprot ID | F1PLV8 |
| Entrez ID | 487036 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_544165.6 |
| Ensembl protein ID | ENSCAFP00000013128 |
| Ensembl nucleotide ID | ENSCAFG00000008925 |
| Gene name | Matrix metallopeptidase 16 |
| Gene symbol | MMP16 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MILLTFSTGR RLDFVHHTGV FFLQTLLWIL CATVCGTEQY FNVEVWLQKY GYLPPTDPRM 60 SVLRSAETMQ AALAAMQQFY GINMTGKVDR NTIDWMKKPR CGVPDQTRGS SKFNIRRKRY 120 ALTGQKWQHK HITYSIKNVT PKVGDPETRK AIRRAFDVWQ NVTPLTFEEV PYSELENGKR 180 DVDITIIFAS GFHGDSSPFD GEGGFLAHAY FPGPGIGGDT HFDSDEPWTL GNPNHDGNDL 240 FLVAVHELGH ALGLEHSNDP TAIMAPFYQY METDNFKLPN DDLQGIQKIY GPPDKIPPPT 300 RPLPTVPPHR SIPPADPRKN DRPKPPRPPT GRPSYPGAKP NICDGNFNTL AILRREMFVF 360 KDQWFWRVRN NRVMDGYPMQ ITYFWRGLPP SIDAVYENSD GNFVFFKGNK YWVFKDTTLQ 420 PGYPHDLITL GSGIPPHGID SAIWWEDVGK TYFFKGDRYW RYSEEMKTMD PGYPKPITVW 480 KGIPESPQGA FVHKENGFTY FYKGKEYWKF NNQILKVEPG YPRSILKDFM GCDGPTDRDK 540 EGHSPPDDVD IVIKLDNTAS TVKAIAIVIP CILALCLLVL VYTVFQFKRK GTPRHILYCK 600 RSMQEWV 607 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MMP16 | 282886 | F1N797 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | MMP16 | 487036 | F1PLV8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | MMP16 | A0A452EG47 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | MMP16 | 4325 | P51512 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Mmp16 | 17389 | Q9WTR0 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | MMP16 | A0A2I3SEA5 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | MMP16 | 100153257 | A0A287AKC1 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | MMP16 | 100101605 | G1T0W4 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Mmp16 | F1M7F5 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0031012 | extracellular matrix |
| GO:0005615 | extracellular space |
| GO:0005887 | integral component of plasma membrane |
| GO:0070006 | metalloaminopeptidase activity |
| GO:0004222 | metalloendopeptidase activity |
| GO:0008270 | zinc ion binding |
| GO:0035988 | chondrocyte proliferation |
| GO:0030574 | collagen catabolic process |
| GO:0097094 | craniofacial suture morphogenesis |
| GO:0048701 | embryonic cranial skeleton morphogenesis |
| GO:0001958 | endochondral ossification |
| GO:0030198 | extracellular matrix organization |
| GO:0016485 | protein processing |
| GO:0001501 | skeletal system development |
| InterPro ID | InterPro Term |
|---|---|
| IPR000585 | Hemopexin-like_dom |
| IPR036375 | Hemopexin-like_dom_sf |
| IPR018487 | Hemopexin-like_repeat |
| IPR018486 | Hemopexin_CS |
| IPR033739 | M10A_MMP |
| IPR024079 | MetalloPept_cat_dom_sf |
| IPR028697 | MMP16 |
| IPR001818 | Pept_M10_metallopeptidase |
| IPR021190 | Pept_M10A |
| IPR021805 | Pept_M10A_metallopeptidase_C |
| IPR021158 | Pept_M10A_Zn_BS |
| IPR006026 | Peptidase_Metallo |
| IPR002477 | Peptidoglycan-bd-like |
| IPR036365 | PGBD-like_sf |