| Tag | Content |
|---|---|
| Uniprot ID | F1Q8Y4 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000042161; ENSDARP00000144985; ENSDARP00000149718; |
| Ensembl nucleotide ID | ENSDARG00000032816; ENSDARG00000116444; |
| Gene name | Transmembrane 7 superfamily member 2 |
| Gene symbol | tm7sf2 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MKPNKHKASH SAEREFGGAL GATCIPVFLP LTVLYLLSVC RSPAASVLQW PPPLPPATHL 60 WDPWAAVLIA GWIALQSFLY LLPIGKVSEG LVLRDGSRLK YPINGFHALS ITAVLLIICI 120 LLGMPLGHLF ELILPLAICA IGVSYLLSMY LYIRSFWAHQ HALSLGGNTG NPLYDFFMGR 180 ELNPRIGNFD LKYFCELRPG LIGWVVINLG MLMKEVELRD SPSLAMLLVN GFQLLYVTDA 240 LWNEEAVLTT MDIVHDGFGF MLAFGDLAWV PFTYSLQAMF LVVHPQSLST LGAVGIVLLN 300 GIGYYIFRRS NSQKNQFRRD PKHKSVAHLE TIATATGKRL LVSGWWGFVR HPNYLGDLLM 360 ALAWSLPCGI SHILPYFYVI YFTILLIHRE ARDEKQCRAK YGVAWDTYCR RVPYRIIPYV 420 Y 421 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TM7SF2 | 282384 | Q17QS8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | TM7SF2 | 476027 | A0A5F4DIJ7 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | TM7SF2 | 100861120 | A0A452DYK9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | TM7SF2 | 7108 | O76062 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Tm7sf2 | 73166 | Q71KT5 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | TM7SF2 | 451314 | K6ZIY4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | 100514510 | A0A480QTI0 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Tm7sf2 | 293688 | Q5BK21 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | tm7sf2 | F1Q8Y4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0030176 | integral component of endoplasmic reticulum membrane |
| GO:0005637 | nuclear inner membrane |
| GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors |
| GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
| GO:0006695 | cholesterol biosynthetic process |
| GO:0016126 | sterol biosynthetic process |
| Keyword ID | Keyword Term |
|---|---|
| KW-0152 | Cholesterol biosynthesis |
| KW-0153 | Cholesterol metabolism |
| KW-0444 | Lipid biosynthesis |
| KW-0443 | Lipid metabolism |
| KW-0472 | Membrane |
| KW-0560 | Oxidoreductase |
| KW-1267 | Proteomics identification |
| KW-1185 | Reference proteome |
| KW-0752 | Steroid biosynthesis |
| KW-0753 | Steroid metabolism |
| KW-0756 | Sterol biosynthesis |
| KW-1207 | Sterol metabolism |
| KW-0812 | Transmembrane |
| KW-1133 | Transmembrane helix |
| Pfam ID | Pfam Term |
|---|---|
| PF01222 | ERG4_ERG24 |