| Tag | Content |
|---|---|
| Uniprot ID | Q17QS8; F1MQ27; |
| Entrez ID | 282384 |
| Genbank protein ID | AAI18203.1 |
| Genbank nucleotide ID | NM_174622.3 |
| Ensembl protein ID | ENSBTAP00000006683 |
| Ensembl nucleotide ID | ENSBTAG00000005069 |
| Gene name | Delta(14)-sterol reductase TM7SF2 |
| Gene symbol | TM7SF2 |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAPPQGSRAP LEFGGPLGAA ALMLLLPVTM FHLLLVARSG PARLLGPPPY LPGLEELWSP 60 WALLLCLTWL GLQAALYLLP ARKVAEGQEL KDKSRLRYPI NGFQALVLTA LLVGLGVSAG 120 LPLSALPEML LPLAFAATLT AFIFSLLLYL KALLAPASAL APGGNSGNLI YDFFLGRELN 180 PRICSFDFKY FCELRPGLIG WVLINLALLI QEAELRGSPS LAMWLVNGFQ LLYVGDALWY 240 EEAVLTTMDI IHDGFGFMLA FGDLAWVPFT YSLQAQFLLY HPQPLGWPLA SFICLINAVG 300 YYIFRGANSQ KNTFRKNPSD PRVADLETIS TATGRRLLVS GWWGMVRHPN YLGDLIMALA 360 WSLPCGVFHL LPYFYFLYFT ALLVHREDRD ERQCRQKYGL AWHEYCRRVP YRIVPYIY 418 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TM7SF2 | 282384 | Q17QS8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | TM7SF2 | 476027 | A0A5F4DIJ7 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | TM7SF2 | 100861120 | A0A452DYK9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | TM7SF2 | 7108 | O76062 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Tm7sf2 | 73166 | Q71KT5 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | TM7SF2 | 451314 | K6ZIY4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | 100514510 | A0A480QTI0 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Tm7sf2 | 293688 | Q5BK21 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | tm7sf2 | F1Q8Y4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0030176 | integral component of endoplasmic reticulum membrane |
| GO:0005637 | nuclear inner membrane |
| GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors |
| GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
| GO:0016126 | sterol biosynthetic process |
| Pfam ID | Pfam Term |
|---|---|
| PF01222 | ERG4_ERG24 |