| Tag | Content |
|---|---|
| Uniprot ID | Q5BK21 |
| Entrez ID | 293688 |
| Genbank protein ID | AAH91237.1; EDM12557.1; |
| Genbank nucleotide ID | NM_001013071.1 |
| Ensembl protein ID | ENSRNOP00000028485 |
| Ensembl nucleotide ID | ENSRNOG00000020989 |
| Gene name | Transmembrane 7 superfamily member 2 |
| Gene symbol | Tm7sf2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MASREASQAP LEFGGPLGVT AMLILLPATM FHLLLAARSG PARLLALPAY LPGLEELWSP 60 RALLLLFIWL GLQVALYLLP ARKVAEGLEL KDKSRLRYPI NGFQALVLTA LLVGLGVSVG 120 LPLGALPGML LPLAFATTLT SFIFSLLLYA KALVAPASAL APGGNSGNSV YDFFLGRELN 180 PRLGSFDFKY FCELRPGLIG WVFINLALLM QEAELRGSPS LAMWLVNGFQ LLYVGDALWY 240 EESVLTTMDI IHDGFGFMLV FGDLAWVPFT YSLQAQFLLY HPQPLGLPMA LLICLIKAVG 300 YYIFRGANSQ KNTFRKNPSD PSVAGLETIP TATGRQLLVS GWWGMVRHPN YLGDLIMALA 360 WSLPCGLSHL LPYFYLLYFT ALLVHREARD EQQCLRKYGR AWQEYCKRVP YRIIPYVY 418 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TM7SF2 | 282384 | Q17QS8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | TM7SF2 | 476027 | A0A5F4DIJ7 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | TM7SF2 | 100861120 | A0A452DYK9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | TM7SF2 | 7108 | O76062 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Tm7sf2 | 73166 | Q71KT5 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | TM7SF2 | 451314 | K6ZIY4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | 100514510 | A0A480QTI0 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Tm7sf2 | 293688 | Q5BK21 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | tm7sf2 | F1Q8Y4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0030176 | integral component of endoplasmic reticulum membrane |
| GO:0005637 | nuclear inner membrane |
| GO:0031090 | organelle membrane |
| GO:0043235 | receptor complex |
| GO:0050613 | delta14-sterol reductase activity |
| GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors |
| GO:0006695 | cholesterol biosynthetic process |
| GO:0016126 | sterol biosynthetic process |
| Pfam ID | Pfam Term |
|---|---|
| PF01222 | ERG4_ERG24 |