| Tag | Content |
|---|---|
| Uniprot ID | F1R8Z8 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000121486 |
| Ensembl nucleotide ID | ENSDARG00000000966 |
| Gene name | Nuclear receptor corepressor 2 |
| Gene symbol | ncor2 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | XNSEKQMRQL AVIPPMLFDA EQQRIKFINM NGLMDDPMKV YKDRQVMNMW SEQEKDTFRE 60 KFIQHPKNFA LIASFLERKT VAECVLFYYL TKKNENYKNI VRRSYRRRGR SQNNQQAQQQ 120 VNRNNQEEKE DKEKEKEGER EEDKAEGDDK EDGIKDDTSG EDGEEKEPPV TVKGRRTANS 180 RGHRKGRVTR SMTNEQEENT SPLGSELANL EMNESSRWTE EEMETAKKGL LQYGRNWSAI 240 AKMVGSKTVS QCKNFYFNYK KRQKLDEILQ QHKIKSEKER KARRKGKAPQ NEEASAPSAA 300 EEEEMEGSGV SGNEEEAQED GEGGANNSSD TESLPSPRSS DDSKVKEEGS ARPKTAPNAT 360 SSSSSTDKDM AAAETGMDEK PKVEKGDGEQ AGVKQEVKTE PGEGASESAG EDKKPPALEV 420 EEGKKEVKKK EHGGKSGAHD SDSSATCSAD EVEETESSEK SRPSLLSFSH DGVISSQAQK 480 PLDLKQLKQR AAAIPPILPE VSGRDNRPGL PGKQAMPDAL ALYQQQITMA HESSQEAKQQ 540 QQQQPTKSQH YPAAGDSGSP RVRTRSPGIS DREREELEGN ERWLQALLHG LHGKKNPGAD 600 DIRALGLGRP VMSSYLSPRD MAKFSQEQLL HYNPSLASTL QPQDRMAAVR PLHIPEPPPL 660 ISSAKPGGSI TQGTPVQLHN PSHGSEHGKV PAPGSLALSW VDQRKMGGFP VVKQEQLSPR 720 GASSSSSQAE NLSTQDSSTS RGPMPAVQGG SITKGIPGTR VHQDSPISYR GGSITQGTPA 780 DVLYKGTITR LINEDSPSRE RSREDTPSKG HVVYEGISGH ILSFERRPNS KEEGCGDVGA 840 GMKRSYDMME VGISSRVPPI RDPLSEGLII RAMPPDRDSP HPQLIRGSIS QGIPRDDCQR 900 REVKQMKREG SPSPRGPGHS TDALKSRSHE SMVPTVKEGG RSIHLIPPEG VVIGKPKEGS 960 ITQGTPLKQE PPGSSKRHDV RSIIASSPRP YSGLPSHLDP RGSDRARYEE AGGKSRPSAV 1020 VSAPSSLSRV SPLALSGEQS SRPHHSPVGY EDHKRSSYPP PSHRASPLSG RENSQRAHEG 1080 SSKPQQQERK ATPTPREMGS TKSPLAVGEH TANLAFERIL GLGPDMYRSQ MSHLTFDAAA 1140 LPRGIPIDSA YYLPRHLAPG PGYPHPYPPY LIRGCFPETA ALENRQTLFN DYITSQQMHQ 1200 WPAAAAMAAQ RPDLLRGLTP REQSLNLAYS PTPRGTSASP MDRITYIPGT SPGFPSGAYN 1260 TSPISPVGAS HMSKIQGGSS SAERERERER EREREQRERE RERERERDRE RDRDREREKD 1320 RDRDRERDKS LSHGNVEHAP IWRPGAPEQM SGSSSRPPSH PYSHQSPLSP RPQDSLQQRP 1380 SVLHNTSSKS LSNSEHNNPS VLRPPGSARY QGFSGHLQRS GLPGEGYPSG TDPSAKDLSR 1440 DGGKSHGRGG LPKHQDLSSS SKSDSKLASP GAGGTYPSPY NQAPVAHLPT SRGHPLLAPE 1500 SGGGGSSIQS RGGDSGSSAS SREKTQNKVM SIQEHELRAL GKTTMTAANF INAIIMHQIS 1560 CDAAMPETGA LATNGTCDAV SAAQQKAFEQ LYGSEDRLSP GQQSSSGVKG SQRVVTLAQH 1620 ISEVITKDYT RQSQQNQIGG QPSLPPGYGY HSSPVLDLTR PPSTPQAQTP TEPNSRYTPE 1680 GTSAERGRDR SPPQNKTSPV SLAADGIEPV SPPGAISEPE TPGANYPNEQ AEQGMGSRSP 1740 ASSSQPPAFF SKLTESNSAI VKSKKEMIKK ISAEAEFNQS QPGTEIFNMP VSTNAGPVSV 1800 RSHPPPEASG NTIGLEAIIR KALMGKYDEQ MDERSPSNSV NSMAAGGAAA VVPPASADGR 1860 SEDPYSLPGK SKGGRSNGRK TKSPGPGLSG GERPSSVSSV HSEGDCNRHT PLTNRVWEDR 1920 PSSTGPTPFP CNPLTMGMRL PSGIMPGPSP SPTHPGASAP TQGQTQPRTW EEEPKPLLCS 1980 QYETLSDSE 1989 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NCOR2 | A0A452E1G4 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | NCOR2 | 9612 | Q9Y618 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ncor2 | 20602 | Q9WU42 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | NCOR2 | H2RC84 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Ncor2 | 360801 | D3ZXN9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ncor2 | F1R8Z8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0000118 | histone deacetylase complex |
| GO:0017053 | transcription repressor complex |
| GO:0042826 | histone deacetylase binding |
| GO:0035257 | nuclear hormone receptor binding |
| GO:0003714 | transcription corepressor activity |
| GO:0060218 | hematopoietic stem cell differentiation |
| GO:0030097 | hemopoiesis |
| GO:0030225 | macrophage differentiation |
| GO:0030099 | myeloid cell differentiation |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0030223 | neutrophil differentiation |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51293 | SANT |
| Pfam ID | Pfam Term |
|---|---|
| PF00249 | Myb_DNA-binding |