| Tag | Content |
|---|---|
| Uniprot ID | F1SRW3 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000005468 |
| Ensembl nucleotide ID | ENSSSCG00000005089 |
| Gene name | Homeobox domain-containing protein |
| Gene symbol | SIX4 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MIASAADIKQ ENGMESSSEG QEAPREVAGG ATAGLSPPAP APFPLEPGDA AAAAARVSGE 60 QGAVSAAAAG AAADQVQLHS ELLGRHHHAV AAAAAAAQTP LAFSPDHVAC VCEALQQGGN 120 LDRLARFLWS LPQSDLLRGN ESLLKARALV AFHQGIYPEL YSILESHSFE SANHPLLQQL 180 WYKARYTEAE RARGRPLGAV DKYRLRRKFP LPRTIWDGEE TVYCFKEKSR NALKELYKQN 240 RYPSPAEKRH LAKITGLSLT QVSNWFKNRR QRDRNPSETQ SKSESDGNPS TEDESSKGHE 300 DLSPHPLSGS SDGVTNLSLS SHMEPVYMQQ IGNAKISLSS SGVLLNGSLV PASTSPVFLN 360 GNSFIQGPNG VILNGLSVGN TQTVSLNPPK MASNIVSNGI SMTDILGSTS QDVKEFKVLQ 420 SSSANSAATT SYSPSTPMSF PGLIPSTEVK REGIQTVASQ DGGSVVTFTT PVQINQYGIV 480 QIPNSGANSQ FLNGSIGFSP LQLPPVSVAA SQGNISINSS TSDGSTFTSE SATVQQGKVF 540 LSSIAPSAVV YTVPNSGQTI GSVKQEGLER SLVFSQLMPV SQNAQVNANL SSESISGSGL 600 HPLSSSLVNV SPTHNFSLTP PTLLNPTELN PDIADGQPMS APVASKSTVT SVSNTNYATL 660 QNCSLITGQD LLSVPMTQAA LGEIVPTAED QVGHPSPTVH QDFGREHHLV MQSVASIKEN 720 FLTNSESKAT SNLMMLDSKS KYVLEGMVET VCEDLETDKK ELAKLQTVQL DEDMQDL 777 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SIX4 | 490720 | F6XRS2 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | SIX4 | 102173941 | A0A452EBD2 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SIX4 | 51804 | Q9UIU6 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Six4 | 20474 | Q61321 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | SIX4 | 452953 | K7A7J5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | SIX4 | F1SRW3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Six4 | 299138 | D3ZAJ7 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0043565 | sequence-specific DNA binding |
| GO:0006355 | regulation of transcription, DNA-templated |