| Tag | Content |
|---|---|
| Uniprot ID | F7CVL4 |
| Entrez ID | 100054550 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_001500370.4 |
| Ensembl protein ID | ENSECAP00000012983 |
| Ensembl nucleotide ID | ENSECAG00000014750 |
| Gene name | Aldehyde dehydrogenase 1 family member A2 |
| Gene symbol | ALDH1A2 |
| Organism | Equus caballus |
| NCBI taxa ID | 9796 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTSSKIEMPG EVKADPAALM ASLHLLPSPT PNLEIKYTKI FINNEWQNSE SGRVFPVYNP 60 ATGEQVCEVQ EADKADIDKA VQAARLAFSL GSVWRRMDAS ERGRLLDKLA DLVERDRAVL 120 ATMESLNGGK PFLQAFYVDL QGVIKTLRYY AGWADKIHGM TIPVDGDYFT FTRHEPIGVC 180 GQIIPWNFPL LMFAWKIAPA LCCGNTVVIK PAEQTPLSAL YMGALIKEAG FPPGVINILP 240 GYGPTAGAAI ASHIGIDKIA FTGSTEVGKL IQEAAGRSNL KRVTLELGGK SPNIIFADAD 300 LDYAVEQAHQ GVFFNQGQCC TAGSRIFVEE SIYEEFVRRS VERAKRRIVG SPFDPTTEQG 360 PQIDKKQYNK ILELIQSGVA EGAKLECGGK GLGRKGFFIE PTVFSNVTDD MRIAKEEIFG 420 PVQEILRFKT MDEVIERANN SDFGLVAAVF TNDINKALTV SSAMQAGTVW INCYNALNAQ 480 SPFGGFKMSG NGREMGEFGL REYSEVKTVT VKIPQKNS 518 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ALDH1A2 | 478319 | F1PGT3 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ALDH1A2 | 102181689 | A0A452G5H4 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ALDH1A2 | 100054550 | F7CVL4 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | ALDH1A2 | 8854 | O94788 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Aldh1a2 | 19378 | Q62148 | CPO,CLO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ALDH1A2 | A0A2I3SDX9 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | ALDH1A2 | I3LK62 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | ALDH1A2 | G1TCP3 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Aldh1a2 | 116676 | Q63639 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | aldh1a2 | Q90Y03 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity |
| GO:0004029 | aldehyde dehydrogenase (NAD+) activity |
| GO:0001758 | retinal dehydrogenase activity |
| GO:0042904 | 9-cis-retinoic acid biosynthetic process |
| GO:0001568 | blood vessel development |
| GO:0048738 | cardiac muscle tissue development |
| GO:0071300 | cellular response to retinoic acid |
| GO:0009855 | determination of bilateral symmetry |
| GO:0031076 | embryonic camera-type eye development |
| GO:0048566 | embryonic digestive tract development |
| GO:0035115 | embryonic forelimb morphogenesis |
| GO:0060324 | face development |
| GO:0030900 | forebrain development |
| GO:0003007 | heart morphogenesis |
| GO:0030902 | hindbrain development |
| GO:0030324 | lung development |
| GO:0016331 | morphogenesis of embryonic epithelium |
| GO:0008285 | negative regulation of cell population proliferation |
| GO:0014032 | neural crest cell development |
| GO:0021915 | neural tube development |
| GO:0030182 | neuron differentiation |
| GO:0031016 | pancreas development |
| GO:0043065 | positive regulation of apoptotic process |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:0010628 | positive regulation of gene expression |
| GO:0051289 | protein homotetramerization |
| GO:0009954 | proximal/distal pattern formation |
| GO:0001936 | regulation of endothelial cell proliferation |
| GO:0034097 | response to cytokine |
| GO:0042574 | retinal metabolic process |
| GO:0090242 | retinoic acid receptor signaling pathway involved in somitogenesis |
| GO:0035799 | ureter maturation |
| Pfam ID | Pfam Term |
|---|---|
| PF00171 | Aldedh |