Gene: tiparp

Basic information

Tag Content
Uniprot ID F8W3Q5
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSDARP00000124327
Ensembl nucleotide ID ENSDARG00000061841
Gene name TCDD-inducible poly(ADP-ribose) polymerase
Gene symbol tiparp
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
XQQMGLADKI PLVKPCFKKK HAQRKLDTKC LRALEDPILS TLLSSDALVS GDGVFVPRNP 60
PRPQRNICTA AVEKQSRISQ VCLKEEDEST DADVAASELA VEQKVTDIQR VSIDANERRF 120
PPQERDEAAP PSDVSGSKLN DIYTAETLQG ANCLAIKEGE IFQDKSEEAS LDLVFELLTQ 180
LQYHTHQGDA VSICVDFLQG VCVYGSDCAQ HHTVLPYHWQ IRRVDTQIWQ SISDDSQEQL 240
ERLYCNPDNE HVRLKFLGRV FTLDFSAMRV CDLEFDLVRR LSTPSSSTST TTPTNTSPTP 300
NCLTVWKYYC RDNFGWREYS EPVVRLIEEA SGRGLKEVRF ITLQNQYILN IREGFQQNAV 360
FGFRRQIKKR PLFRSSIMLT PYLQTLGGLS SAFLSSLETS GNQPLSPTSS TPSKMYPETW 420
LPMNNCQDFM RVPVSRDDRS YRTVYSLFHK TVSETKFRIL KILRVQNPFL WEKYKRKKEY 480
MSRRMTDMDR MLNERHLFHG TSQDVVEGIC KHNFDPRVCG KHATMFGQGS YFARKAVYSH 540
NFSKRSPNGV HYMFLAKVLT GKFTVGNPSM RRPPPLNPRD ASSDLFDSCV DNWMDPQIFV 600
IFNDDQSYPY FIVQYEEVGS TVAI 624

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTIPARP102182170A0A452F6F5Capra hircusPredictionMore>>
1:1 orthologTIPARP25976Q7Z3E1Homo sapiensPredictionMore>>
1:1 orthologTiparp99929Q8C1B2CPOMus musculusPublicationMore>>
1:1 orthologTIPARP460801H2QNM7Pan troglodytesPredictionMore>>
1:1 orthologTIPARP100626111I3LQD6Sus scrofaPredictionMore>>
1:1 orthologTIPARPG1T8C7Oryctolagus cuniculusPredictionMore>>
1:1 orthologTiparp310467D3ZMH5Rattus norvegicusPredictionMore>>
1:1 orthologtiparpF8W3Q5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0008270 zinc ion binding
GO:0071466 cellular response to xenobiotic stimulus

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0479 Metal-binding
KW-1185 Reference proteome
KW-0862 Zinc
KW-0863 Zinc-finger

Interpro

InterPro ID InterPro Term
IPR012317 Poly(ADP-ribose)pol_cat_dom
IPR004170 WWE-dom
IPR018123 WWE-dom_subgr
IPR037197 WWE_dom_sf
IPR000571 Znf_CCCH

PROSITE

PROSITE ID PROSITE Term
PS51059 PARP_CATALYTIC
PS50918 WWE
PS50103 ZF_C3H1

Pfam

Pfam ID Pfam Term
PF00644 PARP
PF02825 WWE