Gene: TIPARP

Basic information

Tag Content
Uniprot ID G1T8C7
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSOCUP00000012819
Ensembl nucleotide ID ENSOCUG00000014910
Gene name TCDD inducible poly(ADP-ribose) polymerase
Gene symbol TIPARP
Organism Oryctolagus cuniculus
NCBI taxa ID 9986
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MEVETTEPEP DCVVQPPSPD DFSCQMRLSE KITPLKTCFK KKQDQKRLGT GTLRSLRPIL 60
NTLLESGSLD GVFRSRDQNA DESSLHEPMV KKPLEINPSC PPTENNMSVL IPDGTNVRGQ 120
IPDAHPSGHA PEQVVPIQDH SFPPETISGT VADATTGHFQ TDLLHSVSSD VPTSPDCIDK 180
VMDYVPGVFQ DNSFTIQYIL DTSDKLSTEL FQDKSEEASL DLVFELVNQL QYHTHQENGI 240
EICMDFLQGT CIYGRDCLKH HTVLPYHWQI KRTTTQKWQS VSNDSQEHLE RFYCNPENDR 300
MRMKYGGQEF WADLNAMNVH ETTEFDQLRR LSTPSSSNVN SIYHTVWKFF CRDHFGWREY 360
PESVIRLIEE ANSRGLKEVR FMMWNNHYIL HNSFFRREIK RRPLFRSCFI LLPYLQTLGG 420
VPTQAPPPLE STSSSQIICP DGVTSANFYP ETWVYMHPSQ DFIQVPVSAE DKSYRIIYNL 480
FHKTVPEFKY RILQILRVQN QFLWEKYKRK KEYMNRKMFG RDRIINERHL FHGTSQDVVD 540
GICKHNFDPR VCGKHATMFG QGHCVPRYKI ASLSLAAMEG DSPQALGSLL PCSETVEVSG 600
SSLTDRKEKN TDEVSKARLW QSTCSPACAS QQDQRISEAT CWIYWPLVMS STNPTLGESH 660
CLHSWSVWSS PAFGPAA 677

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTIPARP102182170A0A452F6F5Capra hircusPredictionMore>>
1:1 orthologTIPARP25976Q7Z3E1Homo sapiensPredictionMore>>
1:1 orthologTiparp99929Q8C1B2CPOMus musculusPublicationMore>>
1:1 orthologTIPARP460801H2QNM7Pan troglodytesPredictionMore>>
1:1 orthologTIPARP100626111I3LQD6Sus scrofaPredictionMore>>
1:1 orthologTIPARPG1T8C7Oryctolagus cuniculusPredictionMore>>
1:1 orthologTiparp310467D3ZMH5Rattus norvegicusPredictionMore>>
1:1 orthologtiparpF8W3Q5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0046872 metal ion binding
GO:0003950 NAD+ ADP-ribosyltransferase activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0479 Metal-binding
KW-1185 Reference proteome
KW-0862 Zinc
KW-0863 Zinc-finger

Interpro

InterPro ID InterPro Term
IPR012317 Poly(ADP-ribose)pol_cat_dom
IPR004170 WWE-dom
IPR037197 WWE_dom_sf
IPR000571 Znf_CCCH

PROSITE

PROSITE ID PROSITE Term
PS51059 PARP_CATALYTIC
PS50918 WWE
PS50103 ZF_C3H1

Pfam

Pfam ID Pfam Term
PF00644 PARP