| Tag | Content |
|---|---|
| Uniprot ID | G1SCM1 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSOCUP00000000099 |
| Ensembl nucleotide ID | ENSOCUG00000000111 |
| Gene name | Collagen type IV alpha 3 chain |
| Gene symbol | COL4A3 |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPGFQGFPGP AGFPGPIGPP GPPGFFGLPG VTGPRGPKGH MGDSVIGQKG DQGVKGLTGP 60 PGPPGTVIVT LTGPANRTDL KGEKGDKGAM GEAGPPGPSG PPGESYGSEK GAPGEPGSQG 120 KPGKDGAPGF PGTEGAKGNR GFPGLTGEVG IKGWKGDIGP PGFRGPTEYY DTYQQKGDEG 180 IPGPPGPKGA RGPQGPVGPP GAPGSPGPSR PGPRGAPGWP GLQGRKGERG PPGKDAVGPP 240 GAPGCPGSPG LLGPPGSPGP PGDVVFRMGP PGDRGLPGHI GFPGIPGLDG PKGEPGLLCT 300 QCPCTPGAPG LPGRPGLDGV KGIPGGQGAA GPKGSPGSPG STGPPGFPGF PGTQGDPGLK 360 GGKGETPEPQ GQAGAPGDPG LRGPPGRKGL AGIPGTPGLK GLPGPRGEPA LSGEKGDQGP 420 PGDPGSPGSP GPAGPAGPPG YGPQGEPGPK GTQGVPGAPG PPGEAGPKGE PSVSTAVPGP 480 PGPPGPPGRA GPQGPPGVPG LKGRCADPGL PGPDGEPGIP GIGFPGPPGP KGDQGFPGTK 540 GSPGCPGEMG KPGIPGKPGL PGAKGEPALA MPGEPGKQGF PGERGNSGEY GEIGLPGLPG 600 RPGIPGKEGL DGPRGDPGQP GPPGETGLPG RCFQGPRGAQ GLPGLNGLMG QPGRRGETGP 660 KGDPGIPGLD RPGFPGEPGP PGMPGHGGEV GPPGPKGYPG NPGFSGPPGE RGKMGMMGYP 720 GTTGPPGLPG SPGYPGRRGS LGIPGVKGQR GPPGDEGERG DRGNPGPARL IQVKGDKGEP 780 GPKGLAGNPG EKGSRGIPGL PGLKGLEGPP GPPGPPGPKG DLGIIGSPGE PGPRGEPGTM 840 GHMGVPGSKG KRGTFGLPGL AGTPGLPGIS GLQGDKGEPG YAEGTRPGPP GPKGDPGLPG 900 DVGKKGERGP PGPPGHSGPA GPAGVPGSPG SPGLPGMPGP DGEMGSKGIK GFPGHPGIKG 960 PPGLPGFPGS PGPVGMRGNQ GHDGIPGPPG EKGETGLLGA HPGPRGHPGA KGAKGDRGAP 1020 GLPGPPGRKG SMGDAGPQGP TGTAGLPGPP GLPGAIIPGQ KGNQGPPGSR GNPGEPGPPG 1080 PPGSQVTGIK GDKGFVGHPG PKGPPGTIGD MGPPGHPGAP GAPGLPGLRG DPGFRGFPGM 1140 RGEKGNPGSP GPTGPPGPTG PKGPPGVRGD PGTLQIISLP GSPGPPGPPG EPGMQGEPGP 1200 PGPPGSPGPC GPKGKPGKDG KPGVPGPAGE KGNKGSKGEQ GPPGSEGLPG MKGKPGDTGP 1260 PAPGTTMRGF VFTRHSQTTA IPSCPEGTEP LYSGFSLLFV QGNEQAHGQD LGTLGSCLQR 1320 FTTMPFLFCN INDVCNFASR NDYSYWLSTP ALMPMDMAPI TGKALEPYIS RCTVCEGPAI 1380 AIAIHSQSTD VPPCPQGWIS LWKGFSFIMF TSAGSEGAGQ ALASPGSCLE EFRANPFIEC 1440 HGRGTCNYYS NSYSFWLASL NPQRMFRKPI PSTVKAGELE KIISRCQVCM KKRH 1494 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | COL4A3 | F1MZU6 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | COL4A3 | 1285 | Q01955 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Col4a3 | 12828 | Q9QZS0 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | COL4A3 | 459988 | H2QJJ5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | COL4A3 | G1SCM1 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Col4a3 | 363265 | F1LRJ1 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005587 | collagen type IV trimer |
| GO:0005783 | endoplasmic reticulum |
| GO:0005201 | extracellular matrix structural constituent |
| GO:0005178 | integrin binding |
| GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process |
| GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway |
| GO:0072577 | endothelial cell apoptotic process |
| GO:0032836 | glomerular basement membrane development |
| GO:0016525 | negative regulation of angiogenesis |
| GO:1905563 | negative regulation of vascular endothelial cell proliferation |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51403 | NC1_IV |