Gene: PHYH

Basic information

Tag Content
Uniprot ID H2Q1M5
Entrez ID 450310
Genbank protein ID
Genbank nucleotide ID XM_507662.4
Ensembl protein ID ENSPTRP00000003892
Ensembl nucleotide ID ENSPTRG00000002302
Gene name Phytanoyl-CoA 2-hydroxylase
Gene symbol PHYH
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MGQRPGGVGV PRAAAMEQPR AAARLQIVLG HLGRPSAGAV VAHPISGTIS SASFHPQQFQ 60
YTLDNNVLTL EQRKFYEENG FLVIKNLVPD ADIQRFRNEF EKICRKEVKP LGLTVMRDVA 120
ISKSEYAPSE KMITKVQDFQ EDKELFRYCT LPEILKYVEC FTGPNIMAMH TMLINKPPDS 180
GKKTSRHPLH QDLHYFPFRP SDLIVCAWTA MEHINRNNGC LVVLPGTHKG SLKPHDYPKW 240
EGGVNKMFHG IQDYEENKAR VHLVMEKGDT VFFHPLLIHG SGQNKTQGFR KAISCHFASA 300
DCHYIDVKGT SQENIEKEVV GIAHKFFGAE NSVDLKDIWM FRARLVKGER TNL 353

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPHYH281400O18778Bos taurusPredictionMore>>
1:1 orthologPHYH102179212A0A452FPA5Capra hircusPredictionMore>>
1:1 orthologPHYH5264O14832Homo sapiensPublicationMore>>
1:1 orthologPhyh16922O35386Mus musculusPredictionMore>>
1:1 orthologPHYH450310H2Q1M5Pan troglodytesPredictionMore>>
1:1 orthologPHYHA0A286ZZ49Sus scrofaPredictionMore>>
1:1 orthologPhyh114209P57093Rattus norvegicusPredictionMore>>
1:1 orthologphyhE7FCS1Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005777 peroxisome
GO:0031406 carboxylic acid binding
GO:0048037 cofactor binding
GO:0008198 ferrous iron binding
GO:0048244 phytanoyl-CoA dioxygenase activity
GO:0006103 2-oxoglutarate metabolic process
GO:0001561 fatty acid alpha-oxidation
GO:0006720 isoprenoid metabolic process
GO:0097089 methyl-branched fatty acid metabolic process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR008775 Phytyl_CoA_dOase

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF05721 PhyH