Gene: TGFA

Basic information

Tag Content
Uniprot ID H2QI26; A0A2J8N4B1; K7DT24;
Entrez ID
Genbank protein ID JAA42522.1
Genbank nucleotide ID XM_009442633.2
Ensembl protein ID ENSPTRP00000020654
Ensembl nucleotide ID ENSPTRG00000012031
Gene name Transforming growth factor alpha
Gene symbol TGFA
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MVPSAGQLAL FALGIVLAAC QALENSTSPL SDPPVAAAVV SHFNDCPDSH TQFCFHGTCR 60
FLVQEDKPAC VCHSGYVGAR CEHADLLAVV AASQKKQAIT ALVVVSIVAL AVLIITCVLI 120
HCCQVRKHCE WCRALICRHE KPSALLKGRT ACCHSETVV 159

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTGFA7039P01135CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologTgfa21802P48030Mus musculusPredictionMore>>
1:1 orthologTGFAH2QI26Pan troglodytesPredictionMore>>
1:1 orthologTGFAF1SLD3Sus scrofaPredictionMore>>
1:1 orthologTgfa24827P01134Rattus norvegicusPredictionMore>>
1:1 orthologtgfaI3ISP4Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016021 integral component of membrane

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1015 Disulfide bond
KW-0245 EGF-like domain
KW-0472 Membrane
KW-1185 Reference proteome
KW-0732 Signal
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom

PROSITE

PROSITE ID PROSITE Term
PS00022 EGF_1
PS01186 EGF_2
PS50026 EGF_3

Pfam

Pfam ID Pfam Term