| Tag | Content |
|---|---|
| Uniprot ID | I3ISP4 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000125933 |
| Ensembl nucleotide ID | ENSDARG00000053939 |
| Gene name | Transforming growth factor, alpha |
| Gene symbol | tgfa |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MMYRAFWDTI FLLTGSLFTY GQVQENSTST TTIATTTTTT TTTTTTTTTS TTTTTTTTRV 60 RKFIAAAVHS HFDDCPDSHS HFCFHGTCRF LILEETPACV CHPGFVGMRC EHADLLAVVA 120 SNHRQQTVAT MLVLCVVGSV MLMLICTLLN CWWRRGGCGR GHTLSCWTEK PRSILTSGTS 180 CCNSETVV 188 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TGFA | 7039 | P01135 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Tgfa | 21802 | P48030 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | TGFA | H2QI26 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | TGFA | F1SLD3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Tgfa | 24827 | P01134 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | tgfa | I3ISP4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0016021 | integral component of membrane |
| GO:0005154 | epidermal growth factor receptor binding |
| GO:0008083 | growth factor activity |
| GO:0000187 | activation of MAPK activity |
| GO:0007173 | epidermal growth factor receptor signaling pathway |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity |
| GO:0045840 | positive regulation of mitotic nuclear division |