Gene: PRDM16

Basic information

Tag Content
Uniprot ID H2R9K2
Entrez ID 457227
Genbank protein ID
Genbank nucleotide ID XM_016952780.1
Ensembl protein ID ENSPTRP00000052931
Ensembl nucleotide ID ENSPTRG00000000059
Gene name PR/SET domain 16
Gene symbol PRDM16
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MRSKARARKL AKSDGDIVNN MYEPNRDLLA SHSAEDEAED SAMSPIPVGP PSPFPTSEDF 60
TPKEGSPYEA PVYIPEDIPI PADFELRESS IPGAGLGVWA KRKMEAGERL GPCVVVPRAA 120
AKETDFGWEQ ILTDVEVSPQ EGCIKKQISE DLGSEKFCVD VNQAGAGSWL KYIRVACSCD 180
DQNLTMCQIS EQIYYKVIKD IEPGEELLVH VKEGVYPLGT VPPGLDEEPT FRCDECDELF 240
QSKLDLRRHK KYTCGSVGAA LYEGLAEELK PEGLGGGSGQ AHECKDCERM FPNKYSLEQH 300
MVIHTEEREY KCDQCPKAFN WKSNLIRHQM SHDSGKRFEC ENCVKVFTDP SNLQRHIRSQ 360
HVGARAHACP DCGKTFTTSS GLKQHKHIHS TVKPFICEVC HKSYTQFSNL CRHKRMHADC 420
RTQIKCKDCG QMFSTTSSLN KHRRFCEGKN HYTPGGIFAP GLPLTPSPMM DKAKPSPGLN 480
HASLGFNEYF PSRPHPGSLP FSTAPPTFPA LTPGFPGIFP PSLYPRPPLL PPTPLLKSPL 540
NHTQDAKLPS PLGNPALPLV SAVSNSSQGT TAAAGPEEKF ESRLEDSCVE KLKTRSSDMS 600
DGSDFEDVNT TTGTDLDTTT GTGSDLDSDV DSDPDKDKGK GKSAEGQPEF GGGLAPPGAP 660
NSMAEVPVFY SQHSFFPPPD EQLLTATGAA GDSIKAIASI AEKYFGPGFM GMQEKKLGSL 720
PYHSAFPFQF LPNFPHSLYP FTDRALAHNL LVKAEPKSPR DALKVGGPSA ECPFDLTTKP 780
KDVKPILPMP KGPSAPASGE EQPLDLSIGS RARASQNGGG REPRKNHVYG ERKLGAGEGL 840
PQVCPARMPQ QPPLHYAKPS PFFMDPIYSR VEKRKVTDPV GALKEKYLRP SPLLFHPQMS 900
AIETMTEKLE SFAAMKADSG SSLQPLPHHP FNFRSPPPTL SDPILRKGKE RYTCRYCGKI 960
FPRSANLTRH LRTHTGEQPY RCKYCDRSFS ISSNLQRHVR NIHNKEKPFK CHLCNRCFGQ 1020
QTNLDRHLKK HEHENAPVSQ HPGVLTNHLG TSASSPTSES DNHALLDEKE DSYFSEIRNF 1080
IANSEMNQAS TRTEKRADMQ IVDGSAQCPG LASEKQEDVV DEDDDDLEEE DEDSLAGKSQ 1140
DDTVSPAPES QAAYEDEEDE EPAASLAVGF DHTRRRMQ 1178

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPRDM16A0A452F1P6Capra hircusPredictionMore>>
1:1 orthologPRDM1663976Q9HAZ2Homo sapiensPredictionMore>>
1:1 orthologPrdm1670673A2A935CPOE14.5Mus musculusPublicationMore>>
1:1 orthologPRDM16457227H2R9K2Pan troglodytesPredictionMore>>
1:1 orthologPrdm16100366024A0A096MJ70Rattus norvegicusPredictionMore>>
1:1 orthologprdm16B8JHX5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0003676 nucleic acid binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0479 Metal-binding
KW-1185 Reference proteome
KW-0862 Zinc
KW-0863 Zinc-finger

Interpro

InterPro ID InterPro Term
IPR001214 SET_dom
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

PROSITE

PROSITE ID PROSITE Term
PS50280 SET
PS00028 ZINC_FINGER_C2H2_1
PS50157 ZINC_FINGER_C2H2_2

Pfam

Pfam ID Pfam Term
PF00096 zf-C2H2