| Tag | Content |
|---|---|
| Uniprot ID | I3L7R2 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005656048.2 |
| Ensembl protein ID | ENSSSCP00000020068 |
| Ensembl nucleotide ID | ENSSSCG00000003527 |
| Gene name | EPH receptor B2 |
| Gene symbol | EPHB2 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGSQSLWYPF LETLMDSTTA TAELGWIVHP PSGWEEVSGY DENMNTIRTY QVCNVFESSQ 60 NNWLRTKFIR RRGAHRIHVE MKFSVRDCSS IPSVPGSCKE TFNLYYYEAD FDSATKTFPN 120 WMENPWVKVD TIAADESFSQ VDLGGRVMKI NTEVRSFGPV SRSGFYLAFQ DYGGCMSLIA 180 VRVFYRKCPR IIQNGAVFQE TLSGAESTSL VAARGSCIAN AEEVDVPIKL YCNGDGEWLV 240 PIGRCMCKAG FEAVENGTVC RGCPSGTFKA NQGDEACTHC PINSRTTSEG ATNCVCRNGY 300 YRADLDPLDM PCTTIPSAPQ AVISSVNETS LMLEWTPPRD SGGREDLVYN IICKSCGSGR 360 GACTRCGDNV QYAPRQLGLT EPRIYISDLL AHTQYTFEIQ AVNGVTDQSP FSPQFASVNI 420 TTNQAAPSAV SIMHQVSRTV DSITLSWSQP DQPNGVILDY ELQYYEKELS EYNATAIKSP 480 TNTVTVQGLK AGAIYVFQVR ARTVAGYGRY SGKMYFQTMT EAEYQTSIQE KLPLIIGSSA 540 AGLVFLIAVV VIAIVCNRRG FERADSEYTD KLQHYTSGHM TPGMKIYIDP FTYEDPNEAV 600 REFAKEIDIS CVKIEQVIGA GEFGEVCSGH LKLPGKREIF VAIKTLKSGY TEKQRRDFLS 660 EASIMGQFDH PNVIHLEGVV TKSTPVMIIT EFMENGSLDS FLRQNDGQFT VIQLVGMLRG 720 IAAGMKYLAD MNYVHRDLAA RNILVNSNLV CKVSDFGLSR FLEDDTSDPT YTSALGGKIP 780 IRWTAPEAIQ YRKFTSASDV WSYGIVMWEV MSYGERPYWD MTNQDVINAI EQDYRLPPPM 840 DCPSALHQLM LDCWQKDRNH RPKFGQIVNT LDKMIRNPNS LKAMAPLSSG INLPLLDRTI 900 PDYTSFNTVD EWLEAIKMGQ YKESFANAGF TSFDVVSQMM MEDILRVGVT LAGHQKKILN 960 SIQVMRAQMN QIQSVEV 977 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EPHB2 | 102186352 | A0A452FQI3 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | EPHB2 | 2048 | P29323 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ephb2 | 13844 | P54763 | CPO | E12.5, E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | EPHB2 | 456613 | K7CN32 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | EPHB2 | I3L7R2 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Ephb2 | A0A0G2JY48 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | ephb2b | 554232 | A2CEJ3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005887 | integral component of plasma membrane |
| GO:0005524 | ATP binding |
| GO:0005003 | ephrin receptor activity |
| InterPro ID | InterPro Term |
|---|---|
| IPR027936 | Eph_TM |
| IPR034238 | EphB2_rcpt_lig-bd |
| IPR001090 | Ephrin_rcpt_lig-bd_dom |
| IPR003961 | FN3_dom |
| IPR036116 | FN3_sf |
| IPR008979 | Galactose-bd-like_sf |
| IPR009030 | Growth_fac_rcpt_cys_sf |
| IPR013783 | Ig-like_fold |
| IPR011009 | Kinase-like_dom_sf |
| IPR000719 | Prot_kinase_dom |
| IPR017441 | Protein_kinase_ATP_BS |
| IPR001660 | SAM |
| IPR013761 | SAM/pointed_sf |
| IPR001245 | Ser-Thr/Tyr_kinase_cat_dom |
| IPR011641 | Tyr-kin_ephrin_A/B_rcpt-like |
| IPR008266 | Tyr_kinase_AS |
| IPR020635 | Tyr_kinase_cat_dom |
| IPR016257 | Tyr_kinase_ephrin_rcpt |
| IPR001426 | Tyr_kinase_rcpt_V_CS |