| Tag | Content |
|---|---|
| Uniprot ID | O42140 |
| Entrez ID | 30227 |
| Genbank protein ID | AAC60252.1; CAP71961.1; |
| Genbank nucleotide ID | NM_131029.2 |
| Ensembl protein ID | ENSDARP00000141078; ENSDARP00000133934; |
| Ensembl nucleotide ID | ENSDARG00000105112; ENSDARG00000111684; |
| Gene name | Netrin-1 |
| Gene symbol | ntn1a |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MLRVSDALVT LVTLCCVLKG TVGGYGMSMF AAQTSPPDPC YDENGHPRRC IPDFVNAAFG 60 KEVRASSTCG KTPSRYCVVT EKGDERHRNC HTCDASDPKK NHPPAYLTDL NNPHNLTCWQ 120 SDNYLQYPQN VTLTLSLGKK FEVTYVSLQF CSPRPESMAI FKSMDYGKSW VPFQYYSTQC 180 RKMYNKPSKA TITKQNEQEA ICTDSHTDMH PLSGGLIAFS TLDGRPSAHD FDNSPVLQDW 240 VTATDIKVTF SRLHTFGDEN EDDSELARDS YFYAVSDLQV GGRCKCNGHA SRCVKDRDGN 300 LVCECKHNTA GPECDRCKPF HYDRPWQRAT AREANECVAC NCNLHARRCR FNMELYKLSG 360 RKSGGVCLNC RHNTAGRHCH YCKEGYYRDM SKPISHRKAC KACDCHPVGA AGKTCNQTTG 420 QCPCKDGVTG ITCNRCANGY QQSRSPIAPC IKIPIAPPTT TASSTEEPSD CESYCKASKG 480 KLKINMKKYC KKDYAVQVHI LKADKAGEWW KFTVNIISVY KQGESRIRRG DQFLWVRAKD 540 VACKCPKIKS GKKYLLLGND EDSPGQSGMV ADKGSLVIQW RDTWARRLRK FQQREKKGKC 600 KKA 603 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NTN1 | 522767 | F1N0C7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | NTN1 | A0A452FGQ4 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | NTN1 | 9423 | O95631 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Ntn1 | 18208 | O09118 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | NTN1 | 455083 | H2QC90 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | A0A4X1V6Z8 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Ntn1 | F1LPC8 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | ntn1a | 30227 | O42140 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005604 | basement membrane |
| GO:0005576 | extracellular region |
| GO:0001525 | angiogenesis |
| GO:0009887 | animal organ morphogenesis |
| GO:0021960 | anterior commissure morphogenesis |
| GO:0033564 | anterior/posterior axon guidance |
| GO:0048846 | axon extension involved in axon guidance |
| GO:0001569 | branching involved in blood vessel morphogenesis |
| GO:0021952 | central nervous system projection neuron axonogenesis |
| GO:0061386 | closure of optic fissure |
| GO:0016358 | dendrite development |
| GO:0003146 | heart jogging |
| GO:0001947 | heart looping |
| GO:0008045 | motor neuron axon guidance |
| GO:0016525 | negative regulation of angiogenesis |
| GO:0048665 | neuron fate specification |
| GO:0071678 | olfactory bulb axon guidance |
| GO:0061626 | pharyngeal arch artery morphogenesis |
| GO:0030516 | regulation of axon extension |
| GO:0030878 | thyroid gland development |
| GO:0009888 | tissue development |
| GO:0001944 | vasculature development |
| GO:0035908 | ventral aorta development |