Tag | Content |
---|---|
Uniprot ID | Q2KJH1 |
Entrez ID | 407216 |
Genbank protein ID | AAI05345.1 |
Genbank nucleotide ID | XM_005211793.3; NM_001045877.1; XM_005211794.3; XM_010809329.2; XM_010809331.2; |
Ensembl protein ID | ENSBTAP00000004992 |
Ensembl nucleotide ID | ENSBTAG00000003835 |
Gene name | Bone morphogenetic protein 4 |
Gene symbol | BMP4 |
Organism | Bos taurus |
NCBI taxa ID | 9913 |
Cleft type | |
Developmental stage | |
Data sources | Homology search |
Reference | |
Functional description | Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). |
Sequence | MIPGNRMLMV VLLCQVLLGG ASHASLIPET GKKKVAEIQG HAGGRRSGQS HELLRDFEAT 60 LLQMFGLRRR PQPSKSAVIP DYMRDLYRLQ SGEEEEEEQI QGIGLEYPER PASRANTVRS 120 FHHEEHLENI PGTSENSAFR FLFNLSSIPE NEVISSAELR LFREQVDQGP DWDQGFHRIN 180 IYEVMKPPAE VVPGHLITRL LDTRLVHHNV TRWETFDVSP AVLRWTREKQ PNYGLAIEVT 240 HLHQTRTHQG QHVRISRSLP QGSGDWAQLR PLLVTFGHDG RGHALTRRRR AKRSPKHHPQ 300 RARKKNKNCR RHSLYVDFSD VGWNDWIVAP PGYQAFYCHG DCPFPLADHL NSTNHAIVQT 360 LVNSVNSSIP KACCVPTELS AISMLYLDEY DKVVLKNYQE MVVEGCGCR 409 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.