| Tag | Content |
|---|---|
| Uniprot ID | Q5J7U3; F1Q0N4; |
| Entrez ID | 450187 |
| Genbank protein ID | AAR99473.1 |
| Genbank nucleotide ID | XM_014119229.1; XM_005628830.2; XM_005628831.2; |
| Ensembl protein ID | ENSCAFP00000011497 |
| Ensembl nucleotide ID | ENSCAFG00000007768 |
| Gene name | Endothelin receptor type A |
| Gene symbol | EDNRA |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | METFCLKVTF WVALVGYVIG DHPESYSTNL STPVDFTTFH GTELSFLVTT HRPTNLALPS 60 NGSMHSYCPQ QTKITSAFKY INTVISCTIF IVGMVGNATL LRIIYQNKCM RNGPNALIAS 120 LALGDLIYVV IDLPINVFKL LAGRWPFDHN DFGVFLCKLF PFLQKSSVGI TVLNLCALSV 180 DRYRAVASWS RVQGIGIPLI TAIEIVSIWI LSFILAIPEA IGFVMVPFEY KGEQHKTCML 240 NATSKFMEFY QDVKDWWLFG FYFCMPLVCT AIFYTLMTCE MLNRRNGSLR IALSEHLKQR 300 REVAKTVFCL VVIFALCWFP LHLSRILKKT VYDEMDKNRC ELLSFLLLMD YIGINLATMN 360 SCINPIALYF VSKKFKNCFQ SCLCCCCYQS KSLMTSVPMN GTSIQWKNHE QNNHNTERSS 420 HKDSIN 426 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EDNRA | 281749 | P21450 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | EDNRA | 450187 | Q5J7U3 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | EDNRA | 102174144 | A0A452FAQ5 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | EDNRA | 100062644 | A0A3Q2HSI2 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | EDNRA | 1909 | P25101 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ednra | 13617 | Q61614 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | EDNRA | 461530 | H2QQ94 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | EDNRA | F1RS70 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | ednrA | 100126073 | A5A8K3 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Ednra | 24326 | A0A0G2JSX5 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0004962 | endothelin receptor activity |
| GO:0007193 | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway |
| GO:0014824 | artery smooth muscle contraction |
| GO:0001569 | branching involved in blood vessel morphogenesis |
| GO:0048484 | enteric nervous system development |
| GO:0060322 | head development |
| GO:0007507 | heart development |
| GO:0001701 | in utero embryonic development |
| GO:0014032 | neural crest cell development |
| GO:0008217 | regulation of blood pressure |
| GO:0010827 | regulation of glucose transmembrane transport |
| GO:0007585 | respiratory gaseous exchange by respiratory system |
| GO:0001666 | response to hypoxia |
| Pfam ID | Pfam Term |
|---|---|
| PF00001 | 7tm_1 |