| Tag | Content |
|---|---|
| Uniprot ID | Q9CQN4; Q8CF09; |
| Entrez ID | 66042 |
| Genbank protein ID | BAB25378.1; AAH21458.1; AAQ83297.1; BAB25333.1; BAC20332.1; BAB22068.1; BAC25193.1; AAN08617.1; BAB21957.1; |
| Genbank nucleotide ID | NM_025312.3 |
| Ensembl protein ID | ENSMUSP00000040230 |
| Ensembl nucleotide ID | ENSMUSG00000036169 |
| Gene name | Sclerostin domain-containing protein 1 |
| Gene symbol | Sostdc1 |
| Organism | Mus musculus |
| NCBI taxa ID | 10090 |
| Cleft type | CPO |
| Developmental stage | |
| Data sources | Manually collected |
| Reference | 30235284; 28692808; |
| Functional description | May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity). Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. |
| Sequence | MLPPAIHLSL IPLLCILMRN CLAFKNDATE ILYSHVVKPV PAHPSSNSTL NQARNGGRHF 60 SSTGLDRNSR VQVGCRELRS TKYISDGQCT SISPLKELVC AGECLPLPVL PNWIGGGYGT 120 KYWSRRSSQE WRCVNDKTRT QRIQLQCQDG STRTYKITVV TACKCKRYTR QHNESSHNFE 180 SVSPAKPAQH HRERKRASKS SKHSLS 206 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
