| Tag | Content |
|---|---|
| Uniprot ID | Q9I9I2 |
| Entrez ID | 30283 |
| Genbank protein ID | AAF64231.1; AAH66498.1; |
| Genbank nucleotide ID | NM_131076.2 |
| Ensembl protein ID | ENSDARP00000090653 |
| Ensembl nucleotide ID | ENSDARG00000014796 |
| Gene name | Protein Wnt |
| Gene symbol | wnt11 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Ligand for members of the frizzled family of seven transmembrane receptors. |
| Sequence | MKRTFPSLPL CLLTFLLLSQ QCTGIRWLAL SQTAQHINKT QHCKTLPGLV SSQAQLCRSN 60 LELMQTIIQA AREVKKVCQK TFTDMRWNCS SIDGPKFLPD LERGTRESAF VYALSAAAIS 120 HTIARACTSG DLRLCSCGPI PGEIPEPGYR WGGCADNIHY GLLMGSKFSD APMKMKKKSG 180 SHANKLMHLH NSEVGRQALR DALVMKCKCH GVSGSCSIRT CWRGLLDLKD IAIDLKTKYL 240 SATKVVHRPM GTRKQLVPKD IDIRPVRENE LVYLQSSPDY CMKNDKLGSF GTQDRQCNKT 300 SSGSDSCDLM CCGRGYNPYT ERVVERCHCK YHWCCYVTCK KCDKTVEKYV CK 352 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | WNT11 | 613288 | F1N4C0 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | WNT11 | 485183 | E2QXQ3 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | WNT11 | 102175498 | A0A452FJS3 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | WNT11 | 7481 | O96014 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Wnt11 | 22411 | P48615 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | WNT11 | 451431 | H2Q4F7 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | WNT11 | I3L5C2 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Wnt-11 | 100009030 | Q27Q51 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Wnt11 | 140584 | G3V819 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | wnt11 | 30283 | Q9I9I2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0005125 | cytokine activity |
| GO:0005109 | frizzled binding |
| GO:0060070 | canonical Wnt signaling pathway |
| GO:0045165 | cell fate commitment |
| GO:0042074 | cell migration involved in gastrulation |
| GO:0048703 | embryonic viscerocranium morphogenesis |
| GO:0007507 | heart development |
| GO:0001947 | heart looping |
| GO:0048884 | neuromast development |
| GO:0030182 | neuron differentiation |
| GO:0060037 | pharyngeal system development |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00246 | WNT1 |
| Pfam ID | Pfam Term |
|---|---|
| PF00110 | wnt |