Gene Page: CELSR2

Summary
GeneID  1952
Symbol  CELSR2
Synonyms  CDHF10|EGFL2|FLJ34118|FLJ42737|FLJ45143|FLJ45845|Flamingo1|KIAA0279|MEGF3
Description  cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
See related  HGNC:3231|MIM:604265|Ensembl:ENSG00000143126|HPRD:05040|
Locus tag  -
Gene type  protein-coding
Map location  1p21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
COPS20.920.89
C11orf580.910.91
YWHAE0.910.88
TAF70.910.89
TIPRL0.900.90
CUL20.900.90
PTGES30.900.89
CNOT70.900.90
PSMD140.900.88
SMNDC10.900.90
Top 10 negatively co-expressed genes
MT-CO2-0.69-0.71
AF347015.8-0.68-0.72
AF347015.2-0.68-0.73
AF347015.31-0.67-0.71
AF347015.15-0.67-0.72
MT-CYB-0.67-0.70
AF347015.33-0.66-0.69
AF347015.27-0.66-0.70
AF347015.26-0.66-0.70
AF347015.21-0.62-0.63
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0004930G-protein coupled receptor activityIEA-
GO:0004930G-protein coupled receptor activityNAS10907856 
GO:0005509calcium ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007218neuropeptide signaling pathwayIEANeurotransmitter (GO term level: 8)-
GO:0048813dendrite morphogenesisISSneurite, dendrite (GO term level: 12)-
GO:0007156homophilic cell adhesionIEA-
GO:0016055Wnt receptor signaling pathwayISS-
GO:0007165signal transductionIEA-
GO:0007275multicellular organismal developmentIEA-
GO:0022407regulation of cell-cell adhesionISS-
GO:0021999neural plate anterioposterior pattern formationISS-
GO:0032583regulation of gene-specific transcriptionISS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmISS-
GO:0016020membraneIEA-
GO:0016021integral to membraneNAS10907856 
GO:0005886plasma membraneIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN 8453All SZGR genes in this pathway
GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN 493298All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP 368234All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
CHOW_RASSF1_TARGETS_DN 2919All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_UP 2115All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_DN 464276All SZGR genes in this pathway
ONDER_CDH1_TARGETS_1_UP 14085All SZGR genes in this pathway
PENG_GLUTAMINE_DEPRIVATION_DN 337230All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C6 3927All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_UP 249170All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_UP 180125All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN 287208All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 528324All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 307185All SZGR genes in this pathway
RIGGINS_TAMOXIFEN_RESISTANCE_UP 6644All SZGR genes in this pathway
STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN 4126All SZGR genes in this pathway
LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_DN 4531All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_DN 593372All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_DN 591366All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_DN 258160All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_DN 270181All SZGR genes in this pathway
AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53 10963All SZGR genes in this pathway
RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP 10457All SZGR genes in this pathway
HOFMANN_MYELODYSPLASTIC_SYNDROM_HIGH_RISK_UP 107All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_DN 13483All SZGR genes in this pathway
STEIN_ESR1_TARGETS 8555All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP 229149All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP 324193All SZGR genes in this pathway
BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP 211131All SZGR genes in this pathway
BHAT_ESR1_TARGETS_VIA_AKT1_UP 281183All SZGR genes in this pathway
GUILLAUMOND_KLF10_TARGETS_UP 5139All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-103/1076636701A,m8hsa-miR-103brainAGCAGCAUUGUACAGGGCUAUGA
hsa-miR-107brainAGCAGCAUUGUACAGGGCUAUCA
miR-125/3513113171Ahsa-miR-125bbrainUCCCUGAGACCCUAACUUGUGA
hsa-miR-125abrainUCCCUGAGACCCUUUAACCUGUG
miR-17-5p/20/93.mr/106/519.d216222m8hsa-miR-17-5pCAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrainUAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106aAAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZUAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZCAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519dCAAAGUGCCUCCCUUUAGAGUGU
miR-193831837m8hsa-miR-193aAACUGGCCUACAAAGUCCCAG
hsa-miR-193bAACUGGCCCUCAAAGUCCCGCUUU
miR-21410101016m8hsa-miR-214brainACAGCAGGCACAGACAGGCAG
miR-3282322381Ahsa-miR-328brainCUGGCCCUCUCUGCCCUUCCGU
miR-4312452511Ahsa-miR-431UGUCUUGCAGGCCGUCAUGCA
miR-485-5p393399m8hsa-miR-485-5pAGAGGCUGGCCGUGAUGAAUUC
miR-93613671Ahsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
miR-96184190m8hsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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