Gene Page

Home
Datasets
Search
Analysis & Tools
Documents
About SZGR
Quick search: (e.g. 207 or AKT)

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

Release Site Map Support Contact us

Gene Page: MOBKL3

Summary

GeneID

25843

Symbol

MOBKL3

Synonyms

2C4D|CGI-95|MGC12264|MOB1|MOB3|PREI3

Description

MOB1, Mps One Binder kinase activator-like 3 (yeast)

Locus tag

Gene type

protein-coding

Map location

2q33.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Expression

P value: 1.62

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

ZNF324B

0.90

0.91

EIF2B5

0.89

TRIM3

0.88

0.90

ZFYVE27

0.88

0.90

STRADA

0.87

0.88

ACAD8

0.87

0.89

SMYD5

0.87

0.88

ATG4B

0.87

0.88

ERCC3

0.87

0.88

COPS7B

0.86

0.87

Top 10 negatively co-expressed genes

AF347015.31

-0.76

-0.77

MT-CO2

-0.76

-0.78

AF347015.8

-0.75

-0.78

AF347015.33

-0.75

AF347015.27

-0.74

-0.77

MT-CYB

-0.74

-0.75

AF347015.21

-0.73

-0.82

AF347015.15

-0.72

-0.74

AF347015.2

-0.72

-0.74

AF347015.26

-0.71

-0.75

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IEA

GO:0005515

protein binding

IPI

17353931

GO:0008270

zinc ion binding

IEA

GO:0046872

metal ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006810

transport

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005794

Golgi apparatus

IEA

GO:0005737

cytoplasm

IEA

GO:0016020

membrane

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ARHGEF15	ARGEF15 \| FLJ13791 \| KIAA0915 \| MGC44868 \| Vsm-RhoGEF	Rho guanine nucleotide exchange factor (GEF) 15	Two-hybrid	BioGRID	16189514
C1orf103	FLJ11269 \| RIF1 \| RP11-96K19.1	chromosome 1 open reading frame 103	Two-hybrid	BioGRID	16169070
CAB39	CGI-66 \| FLJ22682 \| MO25	calcium binding protein 39	Affinity Capture-MS	BioGRID	17353931
CCDC59	BR22 \| DKFZp686K1021 \| FLJ10294 \| HSPC128 \| TAP26	coiled-coil domain containing 59	Affinity Capture-MS	BioGRID	17353931
CCDC85B	DIPA	coiled-coil domain containing 85B	Two-hybrid	BioGRID	16189514
CCT2	99D8.1 \| CCT-beta \| CCTB \| MGC142074 \| MGC142076 \| PRO1633 \| TCP-1-beta	chaperonin containing TCP1, subunit 2 (beta)	Affinity Capture-MS	BioGRID	18782753
CCT3	CCT-gamma \| CCTG \| PIG48 \| TCP-1-gamma \| TRIC5	chaperonin containing TCP1, subunit 3 (gamma)	Affinity Capture-MS	BioGRID	18782753
CCT5	CCT-epsilon \| CCTE \| KIAA0098 \| TCP-1-epsilon	chaperonin containing TCP1, subunit 5 (epsilon)	Affinity Capture-MS	BioGRID	18782753
CCT6A	CCT-zeta \| CCT-zeta-1 \| CCT6 \| Cctz \| HTR3 \| MGC126214 \| MGC126215 \| MoDP-2 \| TCP-1-zeta \| TCP20 \| TCPZ \| TTCP20	chaperonin containing TCP1, subunit 6A (zeta 1)	Affinity Capture-MS	BioGRID	18782753
CCT7	CCT-ETA \| Ccth \| MGC110985 \| Nip7-1 \| TCP-1-eta	chaperonin containing TCP1, subunit 7 (eta)	Affinity Capture-MS	BioGRID	18782753
CCT8	C21orf112 \| Cctq \| D21S246 \| KIAA0002 \| PRED71	chaperonin containing TCP1, subunit 8 (theta)	Affinity Capture-MS	BioGRID	18782753
CRMP1	DPYSL1 \| DRP-1 \| DRP1	collapsin response mediator protein 1	Two-hybrid	BioGRID	16169070
CTTNBP2	C7orf8 \| CORTBP2 \| FLJ34229 \| KIAA1758 \| MGC104579 \| Orf4	cortactin binding protein 2	Affinity Capture-MS	BioGRID	18782753
CTTNBP2NL	DKFZp547A023 \| FLJ13278	CTTNBP2 N-terminal like	Affinity Capture-MS Affinity Capture-Western	BioGRID	18782753
DNM1	DNM	dynamin 1	-	HPRD	11872741
FADD	GIG3 \| MGC8528 \| MORT1	Fas (TNFRSF6)-associated via death domain	Two-hybrid	BioGRID	16169070
FAM40A	FLJ14743 \| KIAA1761 \| MGC148091 \| RP4-773N10.1	family with sequence similarity 40, member A	Affinity Capture-MS	BioGRID	18782753
FAM40B	-	family with sequence similarity 40, member B	Affinity Capture-MS	BioGRID	18782753
FGFR1OP2	DKFZp564O1863 \| HSPC123-like	FGFR1 oncogene partner 2	Affinity Capture-MS	BioGRID	18782753
GDF9	-	growth differentiation factor 9	Two-hybrid	BioGRID	16169070
KIDINS220	ARMS \| MGC163482	kinase D-interacting substrate, 220kDa	Two-hybrid	BioGRID	16169070
MCM2	BM28 \| CCNL1 \| CDCL1 \| D3S3194 \| KIAA0030 \| MGC10606 \| MITOTIN \| cdc19	minichromosome maintenance complex component 2	Two-hybrid	BioGRID	16169070
MED10	L6 \| MGC5309 \| NUT2 \| TRG20	mediator complex subunit 10	Two-hybrid	BioGRID	16169070
MED31	3110004H13Rik \| CGI-125 \| FLJ27436 \| FLJ36714 \| Soh1	mediator complex subunit 31	Two-hybrid	BioGRID	16169070
MYL6	ESMLC \| LC17-GI \| LC17-NM \| LC17A \| LC17B \| MLC1SM \| MLC3NM \| MLC3SM	myosin, light chain 6, alkali, smooth muscle and non-muscle	Two-hybrid	BioGRID	16169070
NME2	MGC111212 \| NDPK-B \| NDPKB \| NM23-H2 \| NM23B \| puf	non-metastatic cells 2, protein (NM23B) expressed in	-	HPRD	11872741
PAICS	ADE2 \| ADE2H1 \| AIRC \| DKFZp781N1372 \| MGC1343 \| MGC5024 \| PAIS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	Two-hybrid	BioGRID	16169070
PDCD10	CCM3 \| MGC1212 \| MGC24477 \| TFAR15	programmed cell death 10	Affinity Capture-MS	BioGRID	18782753
PLEKHM1	AP162 \| B2 \| KIAA0356 \| OPTB6	pleckstrin homology domain containing, family M (with RUN domain) member 1	Two-hybrid	BioGRID	16169070
PPP2CA	PP2Ac \| PP2CA \| RP-C	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	Affinity Capture-MS	BioGRID	18782753
PPP2CB	PP2CB	protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform	Affinity Capture-MS	BioGRID	18782753
PPP2R1A	MGC786 \| PR65A	protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform	Affinity Capture-MS	BioGRID	18782753
PPP2R1B	MGC26454 \| PR65B	protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform	Affinity Capture-MS	BioGRID	18782753
PTPRS	PTPSIGMA	protein tyrosine phosphatase, receptor type, S	Two-hybrid	BioGRID	16169070
RB1CC1	CC1 \| DRAGOU14 \| FIP200	RB1-inducible coiled-coil 1	Affinity Capture-MS	BioGRID	17353931
RP5-1000E10.4	DKFZp686A0768 \| FLJ21168 \| SIKE	suppressor of IKK epsilon	Affinity Capture-MS	BioGRID	18782753
RP6-213H19.1	MASK \| MST4	serine/threonine protein kinase MST4	Affinity Capture-MS	BioGRID	18782753
SCMH1	Scml3	sex comb on midleg homolog 1 (Drosophila)	Two-hybrid	BioGRID	16169070
SETDB1	ESET \| KG1T \| KIAA0067 \| KMT1E	SET domain, bifurcated 1	Two-hybrid	BioGRID	16169070
SLMAP	FLJ42206 \| KIAA1601 \| MGC138760 \| MGC138761 \| SLAP	sarcolemma associated protein	Affinity Capture-MS	BioGRID	18782753
STK24	MST-3 \| MST3 \| MST3B \| STE20 \| STK3	serine/threonine kinase 24 (STE20 homolog, yeast)	Affinity Capture-MS	BioGRID	17353931 \|18782753
STK25	DKFZp686J1430 \| SOK1 \| YSK1	serine/threonine kinase 25 (STE20 homolog, yeast)	Affinity Capture-MS	BioGRID	18782753
STRN	MGC125642 \| SG2NA	striatin, calmodulin binding protein	Affinity Capture-MS Affinity Capture-Western	BioGRID	18782753
STRN3	SG2NA	striatin, calmodulin binding protein 3	Affinity Capture-MS	BioGRID	18782753
STRN4	FLJ35594 \| ZIN \| zinedin	striatin, calmodulin binding protein 4	Affinity Capture-MS	BioGRID	18782753
TCP1	CCT-alpha \| CCT1 \| CCTa \| D6S230E \| TCP-1-alpha	t-complex 1	Affinity Capture-MS	BioGRID	18782753
TIMM13	TIM13 \| TIM13B \| TIMM13A \| TIMM13B \| ppv1	translocase of inner mitochondrial membrane 13 homolog (yeast)	Affinity Capture-MS	BioGRID	17353931
TRAF3IP3	DJ434O14.3 \| FLJ44151 \| MGC117354 \| MGC163289 \| T3JAM	TRAF3 interacting protein 3	Affinity Capture-MS Affinity Capture-Western	BioGRID	18782753
UBE2V2	DDVIT1 \| DDVit-1 \| EDAF-1 \| EDPF-1 \| EDPF1 \| MMS2 \| UEV-2 \| UEV2	ubiquitin-conjugating enzyme E2 variant 2	Two-hybrid	BioGRID	16169070
VHL	HRCA1 \| RCA1 \| VHL1	von Hippel-Lindau tumor suppressor	Affinity Capture-MS	BioGRID	17353931

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
PUIFFE_INVASION_INHIBITED_BY_ASCITES_DN	145	91	All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	722	443	All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	855	609	All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX	795	478	All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_UP	424	268	All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP	314	201	All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN	1237	837	All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_UP	439	257	All SZGR genes in this pathway
ZHANG_BREAST_CANCER_PROGENITORS_UP	425	253	All SZGR genes in this pathway
BONCI_TARGETS_OF_MIR15A_AND_MIR16_1	91	75	All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_UP	518	299	All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP	682	440	All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP	548	370	All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN	1972	1213	All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_EARLY_LATE	317	190	All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP	682	433	All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3	824	528	All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN	784	464	All SZGR genes in this pathway
RAO_BOUND_BY_SALL4	227	149	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
let-7/98	822	828	1A	hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU
miR-101	45	52	1A,m8	hsa-miR-101	UACAGUACUGUGAUAACUGAAG
miR-142-3p	845	852	1A,m8	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA
miR-144	46	52	1A	hsa-miR-144	UACAGUAUAGAUGAUGUACUAG
miR-15/16/195/424/497	269	276	1A,m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-200bc/429	215	221	1A	hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
miR-219	278	284	1A	hsa-miR-219^brain	UGAUUGUCCAAACGCAAUUCU
miR-369-3p	86	92	1A	hsa-miR-369-3p	AAUAAUACAUGGUUGAUCUUU
miR-369-3p	86	92	1A	hsa-miR-369-3p	AAUAAUACAUGGUUGAUCUUU
miR-374	86	92	m8	hsa-miR-374	UUAUAAUACAACCUGAUAAGUG
miR-383	23	29	1A	hsa-miR-383^brain	AGAUCAGAAGGUGAUUGUGGCU
miR-503	270	276	1A	hsa-miR-503	UAGCAGCGGGAACAGUUCUGCAG

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.