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| GeneID |
2906
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| Symbol |
GRIN2D
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| Synonyms |
EB11|NMDAR2D
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| Description |
glutamate receptor, ionotropic, N-methyl D-aspartate 2D |
| See related |
HGNC:4588|MIM:602717|Ensembl:ENSG00000105464|HPRD:04095| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
19q13.1-qter |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| Association | A combined odds ratio method (Sun et al. 2008), association studies | 1 | Link to SZGene | | Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenics, schizophrenia] | Click to show detail | | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 4 | | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.092 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| HSP90B1 | 0.87 | 0.85 | | |
| TM9SF2 | 0.86 | 0.84 | | |
| COPB2 | 0.86 | 0.83 | | |
| SRP54 | 0.86 | 0.86 | | |
| RAB5A | 0.86 | 0.83 | | |
| ATP2C1 | 0.85 | 0.84 | | |
| CANX | 0.85 | 0.83 | | |
| NIPA2 | 0.85 | 0.79 | | |
| CALR | 0.84 | 0.79 | | |
| PSMD1 | 0.83 | 0.83 | | |
Top 10 negatively co-expressed genes | | AF347015.21 | -0.69 | -0.59 | | |
| MT-CO2 | -0.69 | -0.66 | | |
| FXYD1 | -0.67 | -0.62 | | |
| AF347015.33 | -0.66 | -0.64 | | |
| AF347015.31 | -0.66 | -0.64 | | |
| AF347015.8 | -0.65 | -0.63 | | |
| AF347015.2 | -0.64 | -0.65 | | |
| HIGD1B | -0.64 | -0.60 | | |
| IFI27 | -0.63 | -0.60 | | |
| MT-CYB | -0.62 | -0.60 | | |
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| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0004972 | N-methyl-D-aspartate selective glutamate receptor activity | IEA | glutamate (GO term level: 8) | - |
| GO:0005234 | extracellular-glutamate-gated ion channel activity | IEA | glutamate (GO term level: 11) | - |
| GO:0000287 | magnesium ion binding | IEA | | - |
| GO:0004872 | receptor activity | IEA | | - |
| GO:0005509 | calcium ion binding | IEA | | - |
| GO:0005216 | ion channel activity | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0001964 | startle response | IEA | | - |
| GO:0007165 | signal transduction | NAS | | 9480759 |
| GO:0008344 | adult locomotory behavior | IEA | | - |
| GO:0006811 | ion transport | IEA | | - |
| GO:0051930 | regulation of sensory perception of pain | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0019717 | synaptosome | IEA | Synap, Brain (GO term level: 7) | - |
| GO:0045211 | postsynaptic membrane | IEA | Synap, Neurotransmitter (GO term level: 5) | - |
| GO:0045202 | synapse | IEA | neuron, Synap, Neurotransmitter, Glial (GO term level: 2) | - |
| GO:0016021 | integral to membrane | IEA | | - |
| GO:0005886 | plasma membrane | IEA | | - |
| GO:0030054 | cell junction | IEA | | - |
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