Gene Page

Home
Datasets
Search
Analysis & Tools
Documents
About SZGR
Quick search: (e.g. 207 or AKT)

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

Release Site Map Support Contact us

Gene Page: KCNA3

Summary

GeneID

3738

Symbol

KCNA3

Synonyms

HGK5|HLK3|HPCN3|HUKIII|KV1.3|MK3|PCN3

Description

potassium voltage-gated channel, shaker-related subfamily, member 3

Locus tag

Gene type

protein-coding

Map location

1p13.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.0235

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

CLCN4

0.78

0.84

ERC2

0.78

0.86

CLSTN2

0.78

0.87

PRICKLE2

0.77

0.81

ADRBK2

0.77

0.86

HECW2

0.77

0.80

NRCAM

0.76

0.81

ITGA9

0.76

0.81

ZYG11B

0.75

0.82

ASTN1

0.74

0.80

Top 10 negatively co-expressed genes

FXYD1

-0.53

-0.62

RAB34

-0.53

-0.63

TLCD1

-0.51

-0.59

HIGD1B

-0.51

-0.63

AF347015.31

-0.50

-0.61

ACSF2

-0.50

-0.61

MT-CO2

-0.50

-0.63

AF347015.33

-0.50

-0.59

AF347015.21

-0.50

-0.62

SLC25A18

-0.50

-0.58

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IEA

GO:0005244

voltage-gated ion channel activity

TAS

1373731

GO:0005251

delayed rectifier potassium channel activity

TAS

1986382

GO:0030955

potassium ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006811

ion transport

IEA

GO:0006813

potassium ion transport

TAS

1373731

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0016020

membrane

IEA

GO:0016021

integral to membrane

IEA

GO:0008076

voltage-gated potassium channel complex

TAS

1373731

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
KCNA1	AEMK \| EA1 \| HBK1 \| HUK1 \| KV1.1 \| MBK1 \| MGC126782 \| MGC138385 \| MK1 \| RBK1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	Affinity Capture-Western	BioGRID	10428084
KCNA2	HBK5 \| HK4 \| HUKIV \| KV1.2 \| MGC50217 \| MK2 \| NGK1 \| RBK2	potassium voltage-gated channel, shaker-related subfamily, member 2	-	HPRD	12944270
KCNA2	HBK5 \| HK4 \| HUKIV \| KV1.2 \| MGC50217 \| MK2 \| NGK1 \| RBK2		Affinity Capture-Western	BioGRID	10428084
KCNA4	HBK4 \| HK1 \| HPCN2 \| HUKII \| KCNA4L \| KCNA8 \| KV1.4 \| PCN2	potassium voltage-gated channel, shaker-related subfamily, member 4	Affinity Capture-Western	BioGRID	10428084

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
REACTOME_NEURONAL_SYSTEM	279	221	All SZGR genes in this pathway
REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	43	32	All SZGR genes in this pathway
REACTOME_POTASSIUM_CHANNELS	98	68	All SZGR genes in this pathway
LIU_TARGETS_OF_VMYB_VS_CMYB_DN	43	30	All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS	1038	678	All SZGR genes in this pathway
BENPORATH_EED_TARGETS	1062	725	All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3	1118	744	All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS	652	441	All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED	1022	619	All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED	1229	713	All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP	1305	895	All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	1069	729	All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3	349	234	All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3	210	148	All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D	280	158	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-203.1	78	84	m8	hsa-miR-203	UGAAAUGUUUAGGACCACUAG
miR-204/211	600	607	1A,m8	hsa-miR-204^brain	UUCCCUUUGUCAUCCUAUGCCU
miR-204/211	600	607	1A,m8	hsa-miR-211	UUCCCUUUGUCAUCCUUCGCCU
miR-21	800	806	m8	hsa-miR-21^brain	UAGCUUAUCAGACUGAUGUUGA
miR-21	800	806	m8	hsa-miR-590	GAGCUUAUUCAUAAAAGUGCAG
miR-217	879	885	m8	hsa-miR-217	UACUGCAUCAGGAACUGAUUGGAU
miR-218	122	128	m8	hsa-miR-218^brain	UUGUGCUUGAUCUAACCAUGU
miR-30-3p	158	164	m8	hsa-miR-30a-3p	CUUUCAGUCGGAUGUUUGCAGC
miR-30-3p	158	164	m8	hsa-miR-30e-3p	CUUUCAGUCGGAUGUUUACAGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.