Gene Page: SCN9A

Summary
GeneID  6335
Symbol  SCN9A
Synonyms  ETHA|NE-NA|NENA|Nav1.7|PN1
Description  sodium channel, voltage-gated, type IX, alpha subunit
See related  HGNC:10597|MIM:603415|HPRD:04565|
Locus tag  -
Gene type  protein-coding
Map location  2q24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.02395 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
LY6G5B0.680.61
ZNF7890.680.64
CYP2R10.670.66
PBX40.670.67
DONSON0.670.64
ZNF3110.670.67
FBN30.650.69
RANBP170.650.61
ZNF3370.650.62
HPX0.650.52
Top 10 negatively co-expressed genes
FBXO2-0.53-0.61
HLA-F-0.51-0.62
ALDOC-0.50-0.60
AIFM3-0.50-0.60
CLU-0.50-0.60
PTH1R-0.50-0.61
LDHD-0.49-0.59
HLA-E-0.49-0.57
HLA-C-0.49-0.58
PTGDS-0.48-0.61
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005244voltage-gated ion channel activityIEA-
GO:0005248voltage-gated sodium channel activityTAS7720699 
GO:0031402sodium ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0009791post-embryonic developmentIEA-
GO:0006814sodium ion transportTAS7720699 
GO:0006811ion transportIEA-
GO:0006954inflammatory responseIEA-
GO:0048266behavioral response to painIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0001518voltage-gated sodium channel complexIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN 275168All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP 182110All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_DN 291176All SZGR genes in this pathway
JAATINEN_HEMATOPOIETIC_STEM_CELL_UP 316190All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_UP 769437All SZGR genes in this pathway
OKUMURA_INFLAMMATORY_RESPONSE_LPS 183115All SZGR genes in this pathway
MCCABE_BOUND_BY_HOXC6 469239All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
VALK_AML_CLUSTER_3 3312All SZGR genes in this pathway
MIKKELSEN_MEF_ICP_WITH_H3K27ME3 206108All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K4ME3 718401All SZGR genes in this pathway
CHICAS_RB1_TARGETS_CONFLUENT 567365All SZGR genes in this pathway
HOELZEL_NF1_TARGETS_UP 13993All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN 448282All SZGR genes in this pathway
WARTERS_RESPONSE_TO_IR_SKIN 8344All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-18279851Ahsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-9679851Ahsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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