Gene Page: SLAMF1

Summary
GeneID  6504
Symbol  SLAMF1
Synonyms  CD150|CDw150|SLAM
Description  signaling lymphocytic activation molecule family member 1
See related  HGNC:10903|MIM:603492|Ensembl:ENSG00000117090|HPRD:04603|
Locus tag  -
Gene type  protein-coding
Map location  1q22-q23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
COLEC120.710.74
ABCA90.690.70
OLFML10.670.70
KANK20.650.67
CFI0.650.58
TBX180.650.62
LTBR0.650.71
SLC22A60.640.72
ITIH50.640.70
EMILIN20.640.70
Top 10 negatively co-expressed genes
RP9-0.44-0.54
ZNF821-0.43-0.49
ZNF133-0.42-0.46
RPAIN-0.42-0.51
DUSP12-0.42-0.54
DPF1-0.41-0.48
ZNF836-0.41-0.50
ARL9-0.41-0.50
ZNF250-0.41-0.46
MPP3-0.41-0.49
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003823antigen bindingTAS7617038 
GO:0004888transmembrane receptor activityTAS7617038 
GO:0004872receptor activityIEA-
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008284positive regulation of cell proliferationTAS7617038 
GO:0044419interspecies interaction between organismsIEA-
GO:0046649lymphocyte activationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016021integral to membraneIEA-
GO:0009986cell surfaceIEA-
GO:0005886plasma membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
FGRFLJ43153 | MGC75096 | SRC2 | c-fgr | c-src2 | p55c-fgr | p58c-fgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog-HPRD,BioGRID10229804 
FYNMGC45350 | SLK | SYNFYN oncogene related to SRC, FGR, YESReconstituted ComplexBioGRID12545174 
INPP5DMGC104855 | MGC142140 | MGC142142 | SHIP | SHIP1 | SIP-145 | hp51CNinositol polyphosphate-5-phosphatase, 145kDaAffinity Capture-WesternBioGRID10229804 
PTPN11BPTP3 | CFC | MGC14433 | NS1 | PTP-1D | PTP2C | SH-PTP2 | SH-PTP3 | SHP2protein tyrosine phosphatase, non-receptor type 11-HPRD,BioGRID11806999 
CD150 interacts with SHP-2. This interaction was modelled on a demonstrated interaction between human CD150 and monkey SHP-2.BIND11477068 
PTPRCB220 | CD45 | CD45R | GP180 | LCA | LY5 | T200protein tyrosine phosphatase, receptor type, CAffinity Capture-WesternBioGRID10229804 
SH2D1ADSHP | EBVS | FLJ18687 | FLJ92177 | IMD5 | LYP | MTCP1 | SAP | XLP | XLPDSH2 domain protein 1A-HPRD,BioGRID11477068 |11806999 
|12458214 
SLAM interacts with SAP in a phosphorylation-independent manner.BIND10607564 
SH2D1A interacts with CD150.BIND11477068 
SH2D1BEAT2SH2 domain containing 1B-HPRD,BioGRID11689425 
SLAMF1CD150 | CDw150 | SLAMsignaling lymphocytic activation molecule family member 1-HPRD9091591 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
HUTTMANN_B_CLL_POOR_SURVIVAL_DN 6039All SZGR genes in this pathway
MATTIOLI_MGUS_VS_PCL 11662All SZGR genes in this pathway
XU_HGF_TARGETS_REPRESSED_BY_AKT1_DN 9558All SZGR genes in this pathway
DIRMEIER_LMP1_RESPONSE_EARLY 6648All SZGR genes in this pathway
HATADA_METHYLATED_IN_LUNG_CANCER_UP 390236All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM5 9459All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
BASSO_CD40_SIGNALING_UP 10176All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP 390242All SZGR genes in this pathway
SU_THYMUS 2012All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
ZHENG_BOUND_BY_FOXP3 491310All SZGR genes in this pathway
ZHENG_FOXP3_TARGETS_IN_THYMUS_UP 196137All SZGR genes in this pathway
WALLACE_PROSTATE_CANCER_RACE_UP 299167All SZGR genes in this pathway
QI_PLASMACYTOMA_UP 259185All SZGR genes in this pathway
LINDSTEDT_DENDRITIC_CELL_MATURATION_B 5336All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP 338225All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_UP 418282All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN 245150All SZGR genes in this pathway
LEE_DOUBLE_POLAR_THYMOCYTE 2717All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_UP 387225All SZGR genes in this pathway
PILON_KLF1_TARGETS_UP 504321All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_TOP20_UP 2014All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP 271165All SZGR genes in this pathway
HUANG_GATA2_TARGETS_DN 7252All SZGR genes in this pathway
BOSCO_TH1_CYTOTOXIC_MODULE 11462All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.