Gene Page: DLGAP2

Summary
GeneID  9228
Symbol  DLGAP2
Synonyms  DAP2|SAPAP2
Description  discs, large (Drosophila) homolog-associated protein 2
See related  HGNC:2906|MIM:605438|Ensembl:ENSG00000198010|HPRD:09258|
Locus tag  -
Gene type  protein-coding
Map location  8p23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 3 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
EIF60.880.89
EBP0.880.87
TBCB0.880.88
DCTPP10.870.87
DCTN30.860.86
DCTN20.860.88
EEF1B20.850.84
PSMA70.850.86
EIF2B30.850.89
PSMD130.850.87
Top 10 negatively co-expressed genes
AF347015.26-0.68-0.80
MT-CYB-0.68-0.76
AF347015.8-0.67-0.75
AF347015.15-0.67-0.77
AF347015.2-0.67-0.76
AF347015.33-0.67-0.75
AF347015.27-0.66-0.75
MT-CO2-0.66-0.72
AF347015.31-0.65-0.72
AF347015.9-0.62-0.73
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingNAS10759891 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007270nerve-nerve synaptic transmissionNASneuron, Synap (GO term level: 7)9694864 
GO:0007267cell-cell signalingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005883neurofilamentNASneuron, axon (GO term level: 11)10759891 
GO:0045211postsynaptic membraneIEASynap, Neurotransmitter (GO term level: 5)-
GO:0045202synapseIEAneuron, Synap, Neurotransmitter, Glial (GO term level: 2)-
GO:0005886plasma membraneIEA-
GO:0030054cell junctionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DLG1DKFZp761P0818 | DKFZp781B0426 | DLGH1 | SAP97 | dJ1061C18.1.1 | hdlgdiscs, large homolog 1 (Drosophila)hDLG interacts with DAP-2.BIND9286858 
DLG4FLJ97752 | FLJ98574 | PSD95 | SAP90discs, large homolog 4 (Drosophila)-HPRD9286858 
Reconstituted Complex
Two-hybrid		BioGRID9115257 
SHANK2CORTBP1 | CTTNBP1 | ProSAP1 | SHANK | SPANK-3SH3 and multiple ankyrin repeat domains 2Two-hybridBioGRID10527873 
SHANK3KIAA1650 | PROSAP2 | PSAP2 | SPANK-2SH3 and multiple ankyrin repeat domains 3Two-hybridBioGRID10527873 
SORBS2ARGBP2 | FLJ93447 | KIAA0777 | PRO0618sorbin and SH3 domain containing 2-HPRD10521485 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP 332228All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP 195138All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_DN 165106All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
YAGI_AML_WITH_T_8_21_TRANSLOCATION 368247All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 349234All SZGR genes in this pathway
MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 435318All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K27ME3 341243All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-109459511Ahsa-miR-10aUACCCUGUAGAUCCGAAUUUGUG
hsa-miR-10bUACCCUGUAGAACCGAAUUUGU
miR-124.1183718431Ahsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-129-5p18571863m8hsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
hsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
miR-13526512657m8hsa-miR-135aUAUGGCUUUUUAUUCCUAUGUGA
hsa-miR-135bUAUGGCUUUUCAUUCCUAUGUG
miR-15311171123m8hsa-miR-153UUGCAUAGUCACAAAAGUGA
miR-17-5p/20/93.mr/106/519.d156715741A,m8hsa-miR-17-5pCAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrainUAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106aAAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZUAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZCAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519dCAAAGUGCCUCCCUUUAGAGUGU
miR-181187118771Ahsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-182642864341Ahsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-217111911261A,m8hsa-miR-217UACUGCAUCAGGAACUGAUUGGAU
miR-2310341040m8hsa-miR-23abrainAUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrainAUCACAUUGCCAGGGAUUACC
miR-25/32/92/363/367259626031A,m8hsa-miR-25brainCAUUGCACUUGUCUCGGUCUGA
hsa-miR-32UAUUGCACAUUACUAAGUUGC
hsa-miR-92UAUUGCACUUGUCCCGGCCUG
hsa-miR-367AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZUAUUGCACUCGUCCCGGCCUC
miR-323103410401Ahsa-miR-323brainGCACAUUACACGGUCGACCUCU
miR-32619431949m8hsa-miR-326CCUCUGGGCCCUUCCUCCAG
miR-33188918951Ahsa-miR-33GUGCAUUGUAGUUGCAUUG
hsa-miR-33bGUGCAUUGCUGUUGCAUUGCA
miR-381568856941Ahsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-450189218981Ahsa-miR-450UUUUUGCGAUGUGUUCCUAAUA
hsa-miR-450UUUUUGCGAUGUGUUCCUAAUA
miR-9251525211Ahsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
miR-96642764341A,m8hsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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