Gene Page: REC8

Summary
GeneID  9985
Symbol  REC8
Synonyms  HR21spB|MGC950|REC8L1|Rec8p
Description  REC8 homolog (yeast)
See related  HGNC:16879|MIM:608193|Ensembl:ENSG00000100918|HPRD:09739|
Locus tag  -
Gene type  protein-coding
Map location  14q11.2-q12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.047 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
P4HB0.910.89
COPB20.900.88
PDIA40.890.90
CALR0.890.87
CSTF2T0.880.87
SMU10.870.84
G3BP10.870.86
BZW10.870.87
DDB10.870.85
HSPD10.870.83
Top 10 negatively co-expressed genes
MT-CO2-0.70-0.77
AF347015.33-0.69-0.76
AF347015.27-0.68-0.76
FXYD1-0.68-0.75
AF347015.31-0.68-0.76
AF347015.8-0.68-0.76
AF347015.21-0.67-0.72
MT-CYB-0.64-0.73
AF347015.15-0.63-0.74
AF347015.2-0.63-0.73
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007131reciprocal meiotic recombinationTAS10207075 
GO:0007283spermatogenesisTAS10207075 
GO:0007062sister chromatid cohesionTAS10207075 
GO:0007126meiosisTAS10207075 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000228nuclear chromosomeIEA-
GO:0000800lateral elementIEA-
GO:0005634nucleusTAS10207075 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
SMC1ACDLS2 | DKFZp686L19178 | DXS423E | KIAA0178 | MGC138332 | SB1.8 | SMC1 | SMC1L1 | SMC1alpha | SMCBstructural maintenance of chromosomes 1AAffinity Capture-WesternBioGRID12759374 
SMC3BAM | BMH | CDLS3 | CSPG6 | HCAP | SMC3L1structural maintenance of chromosomes 3Affinity Capture-WesternBioGRID12759374 
SYCP3COR1 | MGC71888 | SCP3synaptonemal complex protein 3Affinity Capture-WesternBioGRID12759374 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_OOCYTE_MEIOSIS 11479All SZGR genes in this pathway
REACTOME_MEIOSIS 11681All SZGR genes in this pathway
REACTOME_CELL_CYCLE 421253All SZGR genes in this pathway
REACTOME_CHROMOSOME_MAINTENANCE 12280All SZGR genes in this pathway
REACTOME_MEIOTIC_SYNAPSIS 7357All SZGR genes in this pathway
WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN 199124All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
WANG_HCP_PROSTATE_CANCER 11169All SZGR genes in this pathway
HATADA_METHYLATED_IN_LUNG_CANCER_UP 390236All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN 428306All SZGR genes in this pathway
SANSOM_APC_TARGETS_UP 12684All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
ZHU_CMV_ALL_UP 12089All SZGR genes in this pathway
ZHU_CMV_24_HR_UP 9365All SZGR genes in this pathway
ENGELMANN_CANCER_PROGENITORS_DN 7044All SZGR genes in this pathway
WEBER_METHYLATED_HCP_IN_FIBROBLAST_DN 4222All SZGR genes in this pathway
WEBER_METHYLATED_HCP_IN_SPERM_UP 2013All SZGR genes in this pathway
MATZUK_MEIOTIC_AND_DNA_REPAIR 3926All SZGR genes in this pathway
MATZUK_SPERMATOCYTE 7255All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED 228119All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_DN 841431All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_DN 242146All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
PEDRIOLI_MIR31_TARGETS_UP 221120All SZGR genes in this pathway


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