Gene Page: KATNB1

Summary
GeneID  10300
Symbol  KATNB1
Synonyms  KAT
Description  katanin p80 (WD repeat containing) subunit B 1
See related  HGNC:6217|MIM:602703|Ensembl:ENSG00000140854|HPRD:04081|
Locus tag  -
Gene type  protein-coding
Map location  16q13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
DNM1L0.840.88
TRAPPC6B0.840.85
YWHAB0.820.84
USP140.820.84
RAB6A0.820.85
NKRF0.820.86
VPS410.820.84
SRPK20.820.86
NDFIP10.820.83
UBE2K0.810.86
Top 10 negatively co-expressed genes
AF347015.2-0.61-0.62
MT-CO2-0.60-0.63
EIF4EBP3-0.60-0.67
FXYD1-0.60-0.62
AF347015.31-0.60-0.62
ACSF2-0.59-0.66
AF347015.8-0.59-0.61
AF347015.21-0.58-0.57
HIGD1B-0.57-0.62
METRN-0.57-0.65
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008568microtubule-severing ATPase activityIDA10751153 
GO:0008017microtubule bindingNAS10751153 
GO:0046982protein heterodimerization activityIPI10751153 
GO:0045502dynein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007026negative regulation of microtubule depolymerizationIMP10751153 
GO:0007049cell cycleIEA-
GO:0007067mitosisIEA-
GO:0006605protein targetingNAS10751153 
GO:0051301cell divisionIEA-
GO:0031117positive regulation of microtubule depolymerizationIMP10751153 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0030424axonIEAneuron, axon, Neurotransmitter (GO term level: 6)-
GO:0000922spindle poleIDA10751153 
GO:0005856cytoskeletonIEA-
GO:0005874microtubuleIEA-
GO:0005737cytoplasmIDA10751153 
GO:0008352katanin complexTAS10751153 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
KATNA1-katanin p60 (ATPase-containing) subunit A 1-HPRD10751153 
KATNB1KATkatanin p80 (WD repeat containing) subunit B 1Reconstituted ComplexBioGRID10751153 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN 349157All SZGR genes in this pathway
LAIHO_COLORECTAL_CANCER_SERRATED_DN 8647All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_DN 242165All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_DN 281186All SZGR genes in this pathway
MULLIGHAN_NPM1_SIGNATURE_3_DN 162116All SZGR genes in this pathway
UDAYAKUMAR_MED1_TARGETS_UP 13582All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_DN 536332All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
ROYLANCE_BREAST_CANCER_16Q_COPY_NUMBER_UP 6344All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
CHEOK_RESPONSE_TO_HD_MTX_DN 2418All SZGR genes in this pathway
MUNSHI_MULTIPLE_MYELOMA_UP 8152All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR 544307All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
MARSON_BOUND_BY_E2F4_UNSTIMULATED 728415All SZGR genes in this pathway
HELLER_HDAC_TARGETS_UP 317208All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP 461298All SZGR genes in this pathway
AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G 17196All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP 863514All SZGR genes in this pathway
BOCHKIS_FOXA2_TARGETS 425261All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_1HR_DN 222147All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_DN 254158All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway


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